Neuroblastoma, an embryonal cancer of the autonomic nervous system, is the most common
cancer diagnosed during the first year of life. Although neuroblastoma accounts for …

Cancer is the term used to describe over 100 diseases that share several common
hallmarks. Despite prevention, early detection, and novel therapies, cancer is still the …

Our understanding of how radiation kills normal and tumour cells has been based on an
intimate knowledge of the direct induction of DNA damage and its cellular consequences …

Purpose: To give a state-of-the-art overview on the promise of three-dimensional (3-D)
culture systems for anticancer drug development, with particular emphasis on multicellular …

Non-DNA targeted effects of ionising radiation, which include genomic instability, and a
variety of bystander effects including abscopal effects and bystander mediated adaptive …

Ionising radiation has been an important part of cancer treatment for almost a century, being
used in external-beam radiotherapy, brachytherapy, and targeted radionuclide therapy. At …

Recent studies have shown that indirect effects of ionizing radiation may contribute
significantly to the effectiveness of radiotherapy by sterilizing malignant cells that are not …

Abstract Astatine-211 (211 At, t 1/2= 7.21 h) emitting two α particles with energies of 5.87
and 7.45 MeV, can lead to a high linear energy transfer (LET= 98.84 keV/µm) and short …

Targeted radionuclide therapy (TRT) is used to treat disseminated or metastatic tumours in
which conventional external beam radiotherapy (EBRT) would have unacceptable side …

Wissadula periplocifolia (L.) C. Presl (Malvaceae) is commonly used in Brazil to treat bee
stings and as an antiseptic. The antioxidant properties of its extracts have been previously …