A new era for space life science: international standards for space omics processing

L Rutter, R Barker, D Bezdan, H Cope, SV Costes… - Patterns, 2020 - cell.com
Space agencies have announced plans for human missions to the Moon to prepare for
Mars. However, the space environment presents stressors that include radiation …

[HTML][HTML] Routine omics collection is a golden opportunity for European human research in space and analog environments

H Cope, CRG Willis, MJ MacKay, LA Rutter, LS Toh… - Patterns, 2022 - cell.com
Widespread generation and analysis of omics data have revolutionized molecular medicine
on Earth, yet its power to yield new mechanistic insights and improve occupational health …

From Spaceflight to Mars g-Levels: Adaptive Response of A. Thaliana Seedlings in a Reduced Gravity Environment Is Enhanced by Red-Light Photostimulation

A Villacampa, M Ciska, A Manzano… - International Journal of …, 2021 - mdpi.com
The response of plants to the spaceflight environment and microgravity is still not well
understood, although research has increased in this area. Even less is known about plants' …

Recent transcriptomic studies to elucidate the plant adaptive response to spaceflight and to simulated space environments

A Manzano, E Carnero-Diaz, R Herranz, FJ Medina - Iscience, 2022 - cell.com
Discovering the adaptation mechanisms of plants to the space environment is essential for
supporting human space exploration. Transcriptomic analyses allow the identification of …

Oh G: The x, y and z of human physiological responses to acceleration

RD Pollock, PD Hodkinson… - Experimental Physiology, 2021 - Wiley Online Library
New Findings What is the topic of this review? This review focuses on the main physiological
challenges associated with exposure to acceleration in the Gx, Gy and Gz directions and to …

Space omics research in Europe: Contributions, geographical distribution and ESA member state funding schemes

CS Deane, J Borg, T Cahill, E Carnero-Diaz… - Iscience, 2022 - cell.com
The European research community, via European Space Agency (ESA) spaceflight
opportunities, has significantly contributed toward our current understanding of spaceflight …

Caenorhabditis elegans in microgravity: An omics perspective

A Scott, CRG Willis, M Muratani, A Higashitani… - Iscience, 2023 - cell.com
The application of omics to study Caenorhabditis elegans (C. elegans) in the context of
spaceflight is increasing, illuminating the wide-ranging biological impacts of spaceflight on …

Plants in space: Novel physiological challenges and adaptation mechanisms

FJ Medina, A Manzano, KY Kamal, M Ciska… - Progress in Botany Vol …, 2021 - Springer
Any space exploration initiative, such as the human presence in the Moon and Mars, must
incorporate plants for life support. To enable space plant culture we need to understand how …

Multiscale modeling in the framework of biological systems and its potential for spaceflight biology studies

A Millar-Wilson, Ó Ward, E Duffy, G Hardiman - Iscience, 2022 - cell.com
A central tenet of systems biology is that biological systems are greater than the sum of their
component parts. Spaceflight is associated with hazards including radiation exposure and …

Benchmark dose modeling of transcriptional data: a systematic approach to identify best practices for study designs used in radiation research

R Stainforth, N Vuong, N Adam, B Kuo… - … Journal of Radiation …, 2022 - Taylor & Francis
Purpose Benchmark dose (BMD) modeling is a method commonly used in chemical
toxicology to identify the point of departure (POD) from a dose-response curve linked to a …