DNA damage repair pathways in prostate cancer: a narrative review of molecular mechanisms, emerging biomarkers and therapeutic targets in precision oncology

IM Grypari, V Tzelepi, K Gyftopoulos - International Journal of Molecular …, 2023 - mdpi.com
Prostate cancer (PCa) has a distinct molecular signature, including characteristic
chromosomal translocations, gene deletions and defective DNA damage repair …

Molecular alterations in intraductal carcinoma of the prostate

M Bernhardt, G Kristiansen - Cancers, 2023 - mdpi.com
Simple Summary Intraductal carcinoma of the prostate (IDC-P) is a neoplastic proliferation
within the prostatic ducts with a retained basal cell layer that exceeds the usual extent of …

[HTML][HTML] Cribriform pattern and intraductal carcinoma of the prostate can have a clinicopathological impact, regardless of their percentage and/or number of cores

Y Okubo, S Sato, C Hasegawa, M Koizumi, T Suzuki… - Human Pathology, 2023 - Elsevier
Cribriform pattern and intraductal carcinoma of the prostate (IDC-P) are widely accepted as
poor prognostic factors in prostate cancer. However, it remains unclear to what extent the …

Intraductal Carcinoma of the Prostate: To Grade or Not to Grade

J Surintrspanont, M Zhou - Cancers, 2023 - mdpi.com
Simple Summary Whether intraductal carcinoma of the prostate (IDC-P) should be factored
into prostate cancer (PCa) Grade Group (GG) has been debated vigorously. While there is …

Spectral focusing-based stimulated Raman scattering microscopy using compact glass blocks for adjustable dispersion

JR Gagnon, CH Allen, D Trudel, F Leblond… - Biomedical Optics …, 2023 - opg.optica.org
Spectral focusing is a well-established technique for increasing spectral resolution in
coherent Raman scattering microscopy. However, current methods for tuning optical chirp in …

Leukocytic Infiltration of Intraductal Carcinoma of the Prostate: An Exploratory Study

MK Diop, OE Molina, M Birlea, H LaRue, H Hovington… - Cancers, 2023 - mdpi.com
Simple Summary Men with a particular type of prostate cancer, called intraductal carcinoma
of the prostate (IDC-P), are more likely to die from their cancer than men without IDC-P. No …

Implications of unconventional histological subtypes on magnetic resonance imaging and oncological outcomes in patients who have undergone radical …

K Kurokawa, Y Yamada, S Sakamoto, T Horikoshi… - Scientific Reports, 2024 - nature.com
The prognostic significance of unconventional histology (UH) subtypes including intraductal
carcinoma of the prostate (IDC-P), ductal adenocarcinoma, and cribriform pattern has been …

PTEN loss in intraductal carcinoma of the prostate has low incidence in Japanese patients

T Ito, T Takahara, N Taniguchi… - Pathology …, 2023 - Wiley Online Library
Clinical and genomic features of prostate cancer (PCa) vary considerably between Asian
and Western populations. PTEN loss is the most frequent abnormality in intraductal …

[HTML][HTML] G-Protein-Coupled Receptor-Associated Sorting Protein 1 Overexpression Is Involved in the Progression of Benign Prostatic Hyperplasia, Early-Stage …

C Torres-Luna, S Wei, S Bhattiprolu, G Tuszynski… - Cancers, 2024 - mdpi.com
Abstract Background/Objectives: Prostate cancer (PCa) is a prevalent malignancy,
necessitating accurate diagnostic methods to distinguish it from benign conditions such as …

Is cribriform pattern in prostate biopsy a risk factor for metastatic disease on 68Ga-PSMA-11 PET/CT?

JG Heetman, R Versteeg, L Wever… - World Journal of …, 2023 - Springer
Introduction Cribriform growth pattern (CP) in prostate cancer (PCa) has been associated
with different unfavourable oncological outcomes. This study addresses if CP in prostate …