Interferon regulatory factor 7 in inflammation, cancer and infection

F Qing, Z Liu - Frontiers in Immunology, 2023 - frontiersin.org
Interferon regulatory factor 7 (IRF7), a member of the interferon regulatory factors (IRFs)
family, is located downstream of the pattern recognition receptors (PRRs)-mediated …

The multiple roles of interferon regulatory factor family in health and disease

L Wang, Y Zhu, N Zhang, Y Xian, Y Tang, J Ye… - … and Targeted Therapy, 2024 - nature.com
Abstract Interferon Regulatory Factors (IRFs), a family of transcription factors, profoundly
influence the immune system, impacting both physiological and pathological processes …

Early immune and host cell responses to Cryptosporidium infection

JR Mead - Frontiers in parasitology, 2023 - frontiersin.org
Cryptosporidium spp. are opportunistic protozoan parasites that infect epithelial cells of the
small intestine and cause diarrheal illness in both immunocompetent and immunodeficient …

Identification and characterization of long non-coding RNAs in intestinal immune regulation of largemouth bass, Micropterus salmoides, under acute heat stress

D Yan, X Long, X Zhang, X Dong, Z Wang… - … and Physiology Part D …, 2023 - Elsevier
Long noncoding RNAs (lncRNAs), which are RNA molecules that do not code for proteins
and have a length exceeding 200 base pairs, have been found to play a crucial role in …

Cryptosporidium parvum infection alters the intestinal mucosa transcriptome in neonatal calves: implications for immune function

A Veshkini, F Dengler, L Bachmann… - Frontiers in …, 2024 - frontiersin.org
One of the leading causes of infectious diarrhea in newborn calves is the apicomplexan
protozoan Cryptosporidium parvum (C. parvum). However, little is known about its …

LncRNA Nostrill promotes interferon-γ-stimulated gene transcription and facilitates intestinal epithelial cell-intrinsic anti-Cryptosporidium defense

Z Sharmin, K Jin, AY Gong, S Deng, C Pok… - Frontiers in …, 2024 - frontiersin.org
Intestinal epithelial cells possess the requisite molecular machinery to initiate cell-intrinsic
defensive responses against intracellular pathogens, including intracellular parasites …

c-Myc-induced long noncoding RNA MIRE cooperates with hnRNPK to stabilize ELF2 mRNA and promotes clear cell renal cell carcinogenesis

B Li, B Yao, X Guo, Z Wang, W Xie, X Wu… - Cancer Gene …, 2023 - nature.com
Elevated expression of c-Myc is associated with a variety of human cancers including clear
cell renal cell carcinoma (ccRCC). Increasing evidence suggests that long noncoding RNAs …

Unveiling the Hidden Regulators: The Impact of lncRNAs on Zoonoses

B Xu, Y He, R Yang, J Li, X Wang - International Journal of Molecular …, 2024 - mdpi.com
Zoonoses are diseases and infections naturally transmitted between humans and vertebrate
animals. They form the dominant group of diseases among emerging infectious diseases …

IRF7 Exacerbates Candida albicans Infection by Compromising CD209-Mediated Phagocytosis and Autophagy-Mediated Killing in Macrophages

F Qing, L Sui, W He, Y Chen, L Xu, L He… - The Journal of …, 2024 - journals.aai.org
Abstract IFN regulatory factor 7 (IRF7) exerts anti-infective effects by promoting the
production of IFNs in various bacterial and viral infections, but its role in highly morbid and …

Neospora caninum infection specifically suppresses the expression of a host lncRNA XR_001919077.1 to facilitate parasite propagation by modulating host cell …

SS Zhao, DL Tao, JM Chen, MY Zhang… - Microbiology …, 2024 - journals.asm.org
Neospora caninum is one of the most common pathogens causing reproductive failure in
ruminants (eg, cattle and goats) worldwide. However, due to a poor understanding of the …