The search for antiepileptic compounds with more selective activity and lower toxicity
continues to be an area of intensive investigation in medicinal chemistry. This review …

Epilepsy is a chronic neurological disorder, characterized by the predisposition of
unprovoked seizures affecting the neurobiological, psychological, cognitive, economic, and …

A series of novel pyrazole-phenyl semicarbazone derivatives were designed, synthesized,
and screened for in vitro α-glucosidase inhibitory activity. Given the importance of hydrogen …

Abstract Key compound 2-(4-amino-5-oxo-3-(thiophene-2-ylmethyl)-4, 5-dihydro-1, 2, 4-
tiazole-1-yl) acetohydrazide (3) was synthesized by reacting hydrazine hydrate with ethyl-2 …

Epilepsy is the most common primary neurological disorder known. In the past decade,
various aryl semicarbazones have been designed that were structurally dissimilar from …

Background Nowadays, cancer is an important public health problem in all countries.
Limitations of current chemotherapy for neoplastic diseases such as severe adverse …

Thirty nine new 3, 4-di (substituted) oxy-N2, N5-bis (substituted) thiophene-2, 5-
dicarbohydrazides were synthesized starting from ethyl thiodiglycolate through multi-step …

A number of N-(4, 6-substituted diphenylpyrimidin-2-yl) semicarbazones (4a–t) were
synthesized and tested for their anticonvulsant activity against the two seizure models …

Two novel series of N4-(5-(2/3/4-substituted-phenyl)-1, 3, 4-oxadiazol-2-yl)-N1-(2-methyl-5-
(prop-1-en-2-yl) cyclohex-2-enylidene) semicarbazide and N4-(5-(2/3/4-substituted-phenyl) …

Various 2, 4-dimethoxyphenylsemicarbazones were synthesized starting from 2, 4-
dimethoxyaniline via a phenylcarbamate intermediate. The structures were confirmed by …