Molecular markers for malaria genetic epidemiology: progress and pitfalls
Over recent years, progress in molecular markers for genotyping malaria parasites has
enabled informative studies of epidemiology and transmission dynamics. Results have …
enabled informative studies of epidemiology and transmission dynamics. Results have …
An immune memory–structured SIS epidemiological model for hyperdiverse pathogens
A hyperdiverse class of pathogens of humans and wildlife, including the malaria parasite
Plasmodium falciparum, relies on multigene families to encode antigenic variation. As a …
Plasmodium falciparum, relies on multigene families to encode antigenic variation. As a …
Burkitt lymphoma risk shows geographic and temporal associations with Plasmodium falciparum infections in Uganda, Tanzania, and Kenya
K Broen, J Dickens, R Trangucci… - Proceedings of the …, 2023 - National Acad Sciences
Endemic Burkitt lymphoma (eBL) is a pediatric cancer coendemic with malaria in sub-
Saharan Africa, suggesting an etiological link between them. However, previous cross …
Saharan Africa, suggesting an etiological link between them. However, previous cross …
Neutral vs. non-neutral genetic footprints of Plasmodium falciparum multiclonal infections
At a time when effective tools for monitoring malaria control and eradication efforts are
crucial, the increasing availability of molecular data motivates their application to …
crucial, the increasing availability of molecular data motivates their application to …
Indoor residual spraying with a non-pyrethroid insecticide reduces the reservoir of Plasmodium falciparum in a high-transmission area in northern Ghana
High-malaria burden countries in sub-Saharan Africa are shifting from malaria control
towards elimination. Hence, there is need to gain a contemporary understanding of how …
towards elimination. Hence, there is need to gain a contemporary understanding of how …
Comparison of molecular surveillance methods to assess changes in the population genetics of Plasmodium falciparum in high transmission
A major motivation for developing molecular methods for malaria surveillance is to measure
the impact of control interventions on the population genetics of Plasmodium falciparum as a …
the impact of control interventions on the population genetics of Plasmodium falciparum as a …
Unravelling var complexity: Relationship between DBLα types and var genes in Plasmodium falciparum
The enormous diversity and complexity of var genes that diversify rapidly by recombination
has led to the exclusion of assembly of these genes from major genome initiatives (eg, Pf6) …
has led to the exclusion of assembly of these genes from major genome initiatives (eg, Pf6) …
Measuring changes in Plasmodium falciparum var census population size and structure in response to sequential malaria control interventions
The diversity of Plasmodium falciparum within human hosts requires parasite population
size be defined in terms of parasite variation rather than the number of infected hosts. To …
size be defined in terms of parasite variation rather than the number of infected hosts. To …
Molecular epidemiology of continued Plasmodium falciparum disease transmission after an outbreak in Ecuador
S Ruybal-Pesántez, FE Sáenz, SL Deed… - Frontiers in Tropical …, 2023 - frontiersin.org
To better understand the factors underlying the continued incidence of clinical episodes of
falciparum malaria in E-2025 countries targeting elimination, we characterized the molecular …
falciparum malaria in E-2025 countries targeting elimination, we characterized the molecular …
[HTML][HTML] Hyper-diverse antigenic variation and resilience to transmission-reducing intervention in falciparum malaria
Intervention against falciparum malaria in high transmission regions remains challenging,
with relaxation of control efforts typically followed by rapid resurgence. Resilience to …
with relaxation of control efforts typically followed by rapid resurgence. Resilience to …