Discrete-event simulation (DES) is a stochastic modeling approach widely used to address
dynamic and complex systems, such as healthcare. In this review, academic databases …

Background: The EQ-5D-5L is a generic preference-based questionnaire developed by the
EuroQol Group to measure health-related quality of life (HRQoL) in 2005. Since its …

Health economic evaluations are comparative analyses of alternative courses of action in
terms of their costs and consequences. The Consolidated Health Economic Evaluation …

Chronic wounds have a debilitating effect on the quality of life of many individuals, and the
large economic impact on health system budgets warrants greater attention in policy making …

Objectives The objective of the study is to present the Grading of Recommendations
Assessment, Development, and Evaluation (GRADE) conceptual approach to the …

Background Clinical prediction models are useful in estimating a patient's risk of having a
certain disease or experiencing an event in the future based on their current characteristics …

Methods for measuring and valuing health benefits for economic evaluation and health
technology assessment in adult populations are well developed. In contrast, methods for …

Health technology assessment agencies often prefer that utilities used to calculate quality-
adjusted life years in cost-utility analyses (CUAs) are derived using standardized methods …

Follicular lymphoma (FL) is traditionally considered treatable but incurable. In March 2021,
the US Food and Drug Administration approved the use of chimeric antigen receptor (CAR) …

In the past years, several factors such as evidence-based healthcare culture, quality-linked
incentives, and patient-centered actions, associated with an important increase of financial …