Raman laser intensity and sample clarification on biochemical monitoring over Zika-VLP upstream stages

PE da Silva Cavalcante, JP Rabello, J Leme… - Biochemical and …, 2024 - Elsevier
In the current biopharmaceutical scenario, constant bioprocess monitoring is crucial for the
quality and integrity of final products. Thus, process analytical techniques, such as those …

Chemometrics and analytical blank on the at-line monitoring of Zika-VLP production using near-infrared spectroscopy

JP Rabello, PE da Silva Cavalcante, J Leme… - … Acta Part A: Molecular …, 2025 - Elsevier
The Zika disease caused by the Zika virus was declared a Public Health Emergency by the
World Health Union (WHO), with microcephaly as the most critical consequence. Aiming to …

Limit of detection of Raman spectroscopy using polystyrene particles from 25 to 1000 nm in aqueous suspensions

C Mayorga, S Athalye, M Boodaghidizaji, N Sarathy… - bioRxiv, 2025 - biorxiv.org
Raman spectroscopy is an analytical method capable of detecting various microorganisms
and small particles. Here, we used 25-1000 nm polystyrene particles in aqueous …