Machine learning and integrative analysis of biomedical big data

B Mirza, W Wang, J Wang, H Choi, NC Chung, P Ping - Genes, 2019 - mdpi.com
Recent developments in high-throughput technologies have accelerated the accumulation
of massive amounts of omics data from multiple sources: genome, epigenome …

A review of integrative imputation for multi-omics datasets

M Song, J Greenbaum, J Luttrell IV, W Zhou… - Frontiers in …, 2020 - frontiersin.org
Multi-omics studies, which explore the interactions between multiple types of biological
factors, have significant advantages over single-omics analysis for their ability to provide a …

Integrated omics: tools, advances and future approaches

BB Misra, C Langefeld, M Olivier… - Journal of molecular …, 2019 - jme.bioscientifica.com
With the rapid adoption of high-throughput omic approaches to analyze biological samples
such as genomics, transcriptomics, proteomics, and metabolomics, each analysis can …

The single-cell eQTLGen consortium

MGP van der Wijst, DH De Vries, HE Groot, G Trynka… - elife, 2020 - elifesciences.org
In recent years, functional genomics approaches combining genetic information with bulk
RNA-sequencing data have identified the downstream expression effects of disease …

[HTML][HTML] Making multi-omics data accessible to researchers

A Conesa, S Beck - Scientific data, 2019 - nature.com
A special collection on multi-omics data sharing, launched today at Scientific Data, offers to
the scientific community a compendium of multi-omics datasets ready for reuse, which …

Multiview learning for understanding functional multiomics

ND Nguyen, D Wang - PLoS computational biology, 2020 - journals.plos.org
The molecular mechanisms and functions in complex biological systems currently remain
elusive. Recent high-throughput techniques, such as next-generation sequencing, have …

Metabolomics and multi-omics integration: a survey of computational methods and resources

T Eicher, G Kinnebrew, A Patt, K Spencer, K Ying, Q Ma… - Metabolites, 2020 - mdpi.com
As researchers are increasingly able to collect data on a large scale from multiple clinical
and omics modalities, multi-omics integration is becoming a critical component of …

[HTML][HTML] Metabolomics and modelling approaches for systems metabolic engineering

JK Khanijou, H Kulyk, C Bergès, LW Khoo, P Ng… - Metabolic Engineering …, 2022 - Elsevier
Metabolic engineering involves the manipulation of microbes to produce desirable
compounds through genetic engineering or synthetic biology approaches. Metabolomics …

Integrating omics datasets with the OmicsPLS package

S Bouhaddani, HW Uh, G Jongbloed, C Hayward… - BMC …, 2018 - Springer
Background With the exponential growth in available biomedical data, there is a need for
data integration methods that can extract information about relationships between the data …

BSense: A parallel Bayesian hyperparameter optimized Stacked ensemble model for breast cancer survival prediction

P Kaur, A Singh, I Chana - Journal of Computational Science, 2022 - Elsevier
Breast Cancer is a disease with high risk and mortality rate associated with female health.
The multi-omics data having genome, proteome, transcriptome, metabolome data, and …