Ionic liquids (ILs), due to their inherent structural tunability, outstanding miscibility behavior,
and excellent electrochemical properties, have attracted significant research attention in the …

Protein and peptide drugs are predominantly administered by injection to achieve high
bioavailability, but this greatly compromises patient compliance. Oral and transdermal drug …

In the drug delivery system, the transdermal drug delivery system has the advantages of
painless administration, avoiding the first-pass metabolism, sustained therapeutic effect, and …

Intra/extracellular ion content affects the growth and metastasis of tumor cells, as well as the
efficacy of various antitumor therapies. Herein, a carbonic anhydrase inhibitor (CAI) is …

Ionic liquids (ILs) are innovative ionic solvents with unique properties of negligible vapor
pressure, favorable conductivity, high thermal and chemical stability as well as self …

Ionic liquids (ILs) are a class of nonmolecular compounds composed only of ions.
Compared with traditional organic solvents, ILs have the advantages of wide chemical …

The development of effective drug formulations and delivery systems for newly developed or
marketed drug molecules remains a significant challenge. These drugs can exhibit …

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with different
antigenic variants, has posed a significant threat to public health. It is urgent to develop …

Effective antigen delivery and immune stimulation in nasal mucosa determine the success of
mucosal immunity. Here, an oil-in-ionic liquid (o/IL) nanoemulsion formulated with choline …

Transdermal drug delivery is a promising strategy characterized by minor fluctuations in
blood concentrations, few adverse effects, convenience, and excellent patient compliance …