Recent advances in target characterization and identification by photoaffinity probes

J Sumranjit, SJ Chung - Molecules, 2013 - mdpi.com
Target identification of biologically active molecules such as natural products, synthetic
small molecules, peptides, and oligonucleotides mainly relies on affinity chromatography …

Click chemistry methodology: the novel paintbrush of drug design

I Oprea, TK Smith - ACS Chemical Biology, 2024 - ACS Publications
Click chemistry is an immensely powerful technique for the synthesis of reliable and efficient
covalent linkages. When undertaken in living cells, the concept is thereby coined …

Fluoro aryl azides: synthesis, reactions and applications

E Leyva, MS Platz, SE Loredo-Carrillo… - Current Organic …, 2020 - ingentaconnect.com
Background: The complex photochemistry of aryl azides has fascinated scientists for several
decades. Spectroscopists have investigated the intermediates formed by different analytical …

Copper(I)‐Catalyzed Azide‐Alkyne Cycloaddition Microwave‐Assisted: Preparation of 7‐(4‐Substituted‐1H‐1,2,3‐Triazol‐1‐yl)‐Fluoroquinolones

H Hernández‐López, S Leyva‐Ramos… - …, 2019 - Wiley Online Library
Nowadays, the pharmaceutical industry faces the challenge of innovating and increasing the
productivity of new medicines due to the increasing multidrug resistance among bacteria …

Generic methods for micrometer-and nanometer-scale surface derivatization based on photochemical coupling of primary amines to monolayers of aryl azides on gold …

O El Zubir, I Barlow, E Ul-Haq, HA Tajuddin… - Langmuir, 2013 - ACS Publications
A series of aryl azide terminated thiols and phosphonic acids has been synthesized, and
used to prepare self-assembled monolayers on (respectively) gold and aluminum oxide …

A versatile access to new halogenated 7-azidocoumarins for photoaffinity labeling: Synthesis and photophysical properties

E Pǎunescu, L Louise, L Jean, A Romieu, PY Renard - Dyes and Pigments, 2011 - Elsevier
A versatile methodology for the synthesis of 6/8-halogenated 7-aminocoumarins from the
corresponding 7-hydroxy analogs using Pd-catalyzed amination reaction as the key step is …

Agentes quelantes bifuncionales utilizados en la síntesis de radiofármacos

E Leyva Ramos, S Leyva Ramos… - Revista mexicana de …, 2013 - scielo.org.mx
Los radiofármacos son compuestos orgánicos que contienen átomos de elementos
radiactivos. Se han diseñado para utilizarse en diagnóstico o terapia, para liberar pequeñas …

Dynamics and photophysics of oligomers and polymers

J Pina, T Costa, JSS de Melo - Photochemistry, 2010 - books.google.com
Recent advances in the photophysics of two different type of organic (conjugated and
hydrophobically modified) polymers are reviewed. Three major issues are considered in this …

[PDF][PDF] Fotoquímica de azidas aromáticas: intermediarios, reacciones y su aplicación biológica

DA de Loera Carrera, E Leyva, RJ Cataño - Bol. Soc. Quím. Méx, 2009 - bsqm.org.mx
Las azidas aromáticas pueden descomponerse liberando nitrógeno molecular, generando
intermediarios de tipo nitreno, los cuales pueden llevar a cabo reacciones con importantes …

Entwicklung von Markierungsstrategien für smFRET und PAL am Beispiel der DENV-NS2B-NS3-Protease und ihrer Inhibitoren

A Gellert - 2020 - openscience.ub.uni-mainz.de
Das sich global ausbreitende Dengue Virus (DENV) stellt besonders für Bevölkerungs¬
gruppen der Subtropen und Tropen eine große Herausforderung dar, da es bis heute keine …