Mercury's neurotoxicity is characterized by its disruption of selenium biochemistry
NVC Ralston, LJ Raymond - Biochimica et Biophysica Acta (BBA)-General …, 2018 - Elsevier
Abstract Background Methylmercury (CH 3 Hg+) toxicity is characterized by challenging
conundrums: 1)“selenium (Se)-protective” effects, 2) undefined biochemical mechanism/s of …
conundrums: 1)“selenium (Se)-protective” effects, 2) undefined biochemical mechanism/s of …
[HTML][HTML] Methylmercury's chemistry: From the environment to the mammalian brain
Methylmercury is a neurotoxicant that is found in fish and rice. MeHg's toxicity is mediated by
blockage of-SH and-SeH groups of proteins. However, the identification of MeHg's targets is …
blockage of-SH and-SeH groups of proteins. However, the identification of MeHg's targets is …
Toxic effects of mercury in humans and mammals
G Guzzi, A Ronchi, P Pigatto - Chemosphere, 2021 - Elsevier
Toxic effects of mercury in humans and mammals - ScienceDirect Skip to main contentSkip to
article Elsevier logo Journals & Books Search RegisterSign in View PDF Download full issue …
article Elsevier logo Journals & Books Search RegisterSign in View PDF Download full issue …
[HTML][HTML] Fibromyalgia and nutrition: Therapeutic possibilities?
Fibromyalgia (FM) is a complex chronic condition of unknown etiology, characterized by
deep and widespread pain, sleep problems, cognitive impairment, fatigue, and other well …
deep and widespread pain, sleep problems, cognitive impairment, fatigue, and other well …
Evaluation of dietary selenium, vitamin C and E as the multi-antioxidants on the methylmercury intoxicated mice based on mercury bioaccumulation, antioxidant …
Mercury (Hg) in high exposures can be a potent life threatening heavy metal that
bioaccumulate in aquatic food-chain mainly as organic methylmercury (MeHg). In this …
bioaccumulate in aquatic food-chain mainly as organic methylmercury (MeHg). In this …
Selenium-mercury balance in commercial fish species from the Turkish waters
The interactions between selenium (Se) and mercury (Hg) were assessed in order to
interpret public health risk, associated with dietary mercury exposure due to fish …
interpret public health risk, associated with dietary mercury exposure due to fish …
Maternal seafood consumption is associated with improved selenium status: Implications for child health
NVC Ralston, LJ Raymond, CL Gilman, R Soon… - Neurotoxicology, 2024 - Elsevier
Selenium (Se) is required for synthesis of selenocysteine (Sec), an amino acid expressed in
the active sites of Se-dependent enzymes (selenoenzymes), including forms with essential …
the active sites of Se-dependent enzymes (selenoenzymes), including forms with essential …
Should ebselen be considered for the treatment of mercury intoxication? A minireview
Mercury is a ubiquitous environmental contaminant and can be found in inorganic (Hg0,
Hg+ and Hg2+) and organic forms (chiefly CH3Hg+ or MeHg+). The main route of human …
Hg+ and Hg2+) and organic forms (chiefly CH3Hg+ or MeHg+). The main route of human …
Effects of soft electrophiles on selenium physiology
NVC Ralston - Free Radical Biology and Medicine, 2018 - Elsevier
This review examines the effects of neurotoxic electrophiles on selenium (Se) metabolism.
Selenium-dependent enzymes depend on the unique and elite functions of selenocysteine …
Selenium-dependent enzymes depend on the unique and elite functions of selenocysteine …
Disruption of selenium transport and function is a major contributor to mercury toxicity in zebrafish larvae
NV Dolgova, S Nehzati, TC MacDonald… - Metallomics, 2019 - academic.oup.com
Mercury is one of the most toxic elements threatening the biosphere, with levels steadily
rising due to both natural and human activities. Selenium is an essential micronutrient …
rising due to both natural and human activities. Selenium is an essential micronutrient …