An increasing evidence suggests that vanadium compounds are novel potential drugs in the
treatment of diabetes, atherosclerosis, and cancer. Vanadium has also demonstrated …

Critical illness in COVID-19 is an extreme and clinically homogeneous disease phenotype
that we have previously shown to be highly efficient for discovery of genetic associations …

INTRODUCTION Interferons (IFNs) are cytokines that are rapidly deployed in response to
invading pathogens. By initiating a signaling cascade that stimulates the expression of …

Genome-wide association studies (GWASs) are a research approach used to identify
genetic variants associated with common diseases, like COVID-19. The lead genetic …

Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic
variation influences the development of illness requiring critical care or hospitalization,–after …

Metabolic pathways regulate immune responses and disrupted metabolism leads to immune
dysfunction and disease. Coronavirus disease 2019 (COVID-19) is driven by imbalanced …

Immunopathology occurs in the lung and spleen in fatal coronavirus disease (COVID-19),
involving monocytes/macrophages and plasma cells. Antiinflammatory therapy reduces …

SARS-CoV-2 infection causes COVID-19, a severe acute respiratory disease associated
with cardiovascular complications including long-term outcomes. The presence of virus in …

SARS-CoV-2 is the virus causing the major pandemic facing the world today. Although,
SARS-CoV-2 primarily causes lung infection, a variety of symptoms have proven a systemic …

In December 2019, a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
started spreading worldwide causing the coronavirus disease 2019 (COVID-19) pandemic …