The pathogenesis of foot-and-mouth disease in pigs

C Stenfeldt, F Diaz-San Segundo… - Frontiers in veterinary …, 2016 - frontiersin.org
The greatest proportion of foot-and-mouth disease (FMD) clinical research has been
dedicated to elucidating pathogenesis and enhancing vaccine protection in cattle with less …

Differential persistence of foot-and-mouth disease virus in African buffalo is related to virus virulence

F Maree, LM de Klerk-Lorist, S Gubbins… - Journal of …, 2016 - Am Soc Microbiol
Foot-and-mouth disease (FMD) virus (FMDV) circulates as multiple serotypes and strains in
many regions of endemicity. In particular, the three Southern African Territories (SAT) …

Foot-and-mouth disease virus persists in the light zone of germinal centres

N Juleff, M Windsor, E Reid, J Seago, Z Zhang… - PloS one, 2008 - journals.plos.org
Foot-and-mouth disease virus (FMDV) is one of the most contagious viruses of animals and
is recognised as the most important constraint to international trade in animals and animal …

Foot-and-Mouth Disease Virus Can Induce a Specific and Rapid CD4+ T-Cell-Independent Neutralizing and Isotype Class-Switched Antibody Response in Naïve …

N Juleff, M Windsor, EA Lefevre, S Gubbins… - Journal of …, 2009 - Am Soc Microbiol
The role of T-lymphocyte subsets in recovery from foot-and-mouth disease virus (FMDV)
infection in calves was investigated by administering subset-specific monoclonal antibodies …

Evolution of foot-and-mouth disease virus intra-sample sequence diversity during serial transmission in bovine hosts

MJ Morelli, CF Wright, NJ Knowles, N Juleff… - Veterinary …, 2013 - Springer
RNA virus populations within samples are highly heterogeneous, containing a large number
of minority sequence variants which can potentially be transmitted to other susceptible hosts …

Virus excretion from foot-and-mouth disease virus carrier cattle and their potential role in causing new outbreaks

ABR Parthiban, M Mahapatra, S Gubbins, S Parida - PloS one, 2015 - journals.plos.org
The role of foot-and-mouth disease virus (FMDV) carrier cattle in causing new outbreaks is
still a matter of debate and it is important to find out these carrier animals by post-outbreak …

The effect of vaccination on foot and mouth disease virus transmission among dairy cows

K Orsel, MCM De Jong, A Bouma, JA Stegeman… - Vaccine, 2007 - Elsevier
The aim of this study was to quantify the effect of a single vaccination of dairy cows on foot
and mouth disease virus (FMDV) transmission. To estimate if vaccination could significantly …

Picornaviruses

S Alexandersen, NJ Knowles, GJ Belsham… - Diseases of …, 2019 - Wiley Online Library
Picornaviruses are small, roughly spherical viruses with a protein shell. The picornavirus
genome includes two untranslated regions, one preceding and one following the single …

Modeling inoculum dose dependent patterns of acute virus infections

Y Li, A Handel - Journal of theoretical biology, 2014 - Elsevier
Inoculum dose, ie the number of pathogens at the beginning of an infection, often affects key
aspects of pathogen and immune response dynamics. These in turn determine clinically …

Development of foot-and-mouth disease virus (FMDV) serotype O virus-like-particles (VLPs) vaccine and evaluation of its potency

BM Subramanian, M Madhanmohan, R Sriraman… - Antiviral research, 2012 - Elsevier
Foot-and-mouth disease (FMD) is an economically significant viral disease that rampage
dairy and other livestock industries in many countries. The disease is being controlled by the …