[HTML][HTML] Therapeutic applications of selenium nanoparticles
Nanoparticles (NPs) serve to reduce the toxicity, enhance bioactivity, improve targeting, and
provide versatile means to control the release profile of the encapsulated moiety. Among …
provide versatile means to control the release profile of the encapsulated moiety. Among …
Pulmonary fibrosis as a result of acute lung inflammation: molecular mechanisms, relevant in vivo models, prognostic and therapeutic approaches
IA Savin, MA Zenkova, AV Sen'kova - International Journal of Molecular …, 2022 - mdpi.com
Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …
Apoptosis and pharmacological therapies for targeting thereof for cancer therapeutics
Apoptosis is an evolutionarily conserved sequential process of cell death to maintain a
homeostatic balance between cell formation and cell death. It is a vital process for normal …
homeostatic balance between cell formation and cell death. It is a vital process for normal …
[HTML][HTML] A novel pathophysiological classification of silicosis models provides some new insights into the progression of the disease
Z Cao, M Song, Y Liu, J Pang, Z Li, X Qi, T Shu… - Ecotoxicology and …, 2020 - Elsevier
Silicosis is caused by massive inhalation of silica-based particles, which leads to pulmonary
inflammation, pulmonary fibrosis and lung dysfunction. Currently, the pathophysiological …
inflammation, pulmonary fibrosis and lung dysfunction. Currently, the pathophysiological …
[HTML][HTML] Withaferin-A attenuates multiple low doses of Streptozotocin (MLD-STZ) induced type 1 diabetes
Type 1 diabetes mellitus (T1DM) is one of the major metabolic disorders with life-long
dependence on insulin. The present study was designed to evaluate the antioxidant and anti …
dependence on insulin. The present study was designed to evaluate the antioxidant and anti …
Ferulic acid ameliorates the progression of pulmonary fibrosis via inhibition of TGF-β/smad signalling
Natural products are one of the best sources for the discovery of novel drugs and
compounds for multiple diseases. Pulmonary fibrosis (PF) is a chronic, progressive …
compounds for multiple diseases. Pulmonary fibrosis (PF) is a chronic, progressive …
Superoxide dismutase mimetic nanoceria restrains cerulein induced acute pancreatitis
Aim: The present study was carried out to assess the effect of nanoceria (NC) on pancreatic
inflammation caused by cerulein. Methods: NC was characterized and in vitro studies were …
inflammation caused by cerulein. Methods: NC was characterized and in vitro studies were …
[HTML][HTML] Visnagin attenuates acute pancreatitis via Nrf2/NFκB pathway and abrogates associated multiple organ dysfunction
Acute pancreatitis (AP) is an exocrine dysfunction of the pancreas where oxidative stress
and inflammatory cytokines play a key role in induction and progression of the disease …
and inflammatory cytokines play a key role in induction and progression of the disease …
Yttrium oxide nanoparticles reduce the severity of acute pancreatitis caused by cerulein hyperstimulation
Oxidative stress plays a major role in acute pancreatitis (AP), leading to massive
macrophage infiltration. Nanoyttria (NY) possesses potent free radical scavenging activity …
macrophage infiltration. Nanoyttria (NY) possesses potent free radical scavenging activity …
Nimbolide ameliorates unilateral ureteral obstruction-induced renal fibrosis by inhibition of TGF-β and EMT/Slug signalling
Chronic kidney disease (CKD) involves interstitial fibrosis as an underlying pathological
process associated with compromised renal function irrespective of etiological cause of the …
process associated with compromised renal function irrespective of etiological cause of the …