Cardiac patches are biomaterials that can be used for transplantation and repair of
damaged myocardium by combining seed cells with the ability to form cardiomyocytes and …

SARS-CoV-2 infection has led to a global health crisis, and yet our understanding of the
disease and potential treatment options remains limited. The infection occurs through …

Cardiac transcription factors orchestrate a regulatory network controlling cardiovascular
development. Isl1, a LIM-homeodomain transcription factor, acts as a key player in multiple …

Aims We prospectively isolate and characterize first and second heart field-and nodal-like
cardiomyocytes using a double reporter line from human embryonic stem cells. Our double …

The T-box factors belong to an ancient protein family, which comprises a cluster of
evolutionarily-conserved transcription factors that regulate gene expression and that are …

Mammary and extramammary Paget's Diseases (PD) are a malignant skin cancer
characterized by the appearance of Paget cells. Although easily diagnosed, its …

As an evidence-based performance, the rising incidence of various ischemic disorders has
been observed across many nations. As a result, there is a growing need for the …

Regenerative medicine now needs to pass a crucial turning point, from academic research
to the market. Several sources/types of cells have been experimented with, more or less …

Stem cells and their derivatives are novel pharmaceutics that have the potential for use as
tissue replacement therapies. However, the heterogeneous characteristics of stem cell …

Human embryonic stem cells (hESCs) have the capacity for self-renewal and multilineage
differentiation, which are of clinical importance for regeneration medicine. Despite the …