Enhanced neutralization of SARS-CoV-2 variant BA. 2.86 and XBB sub-lineages by a tetravalent COVID-19 vaccine booster

X Wang, S Jiang, W Ma, X Li, K Wei, F Xie, C Zhao… - Cell host & …, 2024 - cell.com
Summary Emerging SARS-CoV-2 sub-lineages like XBB. 1.5, XBB. 1.16, EG. 5, HK. 3 (FLip),
and XBB. 2.3 and the variant BA. 2.86 have recently been identified. Understanding the …

Should SARS-CoV-2 serological testing be used in the decision to deliver a COVID-19 vaccine booster? A pro-con assessment

M Augello, I Wagenhäuser, M Krone, N Dauby… - Vaccine, 2024 - Elsevier
Abstract Anti–SARS-CoV-2 vaccination has saved millions of lives in the past few years. To
maintain a high level of protection, particularly in at-risk populations, booster doses are …

SARS-CoV-2 Omicron: Viral Evolution, Immune Evasion, and Alternative Durable Therapeutic Strategies

H Guo, S Ha, JW Botten, K Xu, N Zhang, Z An… - Viruses, 2024 - mdpi.com
Since the SARS-CoV-2 Omicron virus has gained dominance worldwide, its continual
evolution with unpredictable mutations and patterns has revoked all authorized …

Vaccination impairs de novo immune response to omicron breakthrough infection, a precondition for the original antigenic sin

J Pušnik, J Zorn, WO Monzon-Posadas… - Nature …, 2024 - nature.com
Several studies have suggested the imprinting of SARS-CoV-2 immunity by original immune
challenge without addressing the formation of the de novo response to successive antigen …

[HTML][HTML] Humoral and cellular immune responses following Omicron BA. 2.2 breakthrough infection and Omicron BA. 5 reinfection

XJ Zhao, B Ji, C Shang, DY Li, S Zhang, HJ Gu… - Iscience, 2024 - cell.com
The emergence of novel Omicron subvariants has raised concerns regarding the efficacy of
immunity induced by prior Omicron subvariants breakthrough infection (BTI) or reinfection …

Sustained S-IgG and S-IgA antibodies to Moderna's mRNA-1273 vaccine in a Sub-Saharan African cohort suggests need for booster timing reconsiderations

J Serwanga, V Ankunda, JS Katende, C Baine… - Frontiers in …, 2024 - frontiersin.org
Introduction This study sought to elucidate the long-term antibody responses to the Moderna
mRNA-1273 COVID-19 vaccine within a Ugandan cohort, aiming to contribute to the sparse …

Effect of XBB. 1.5-adapted booster vaccination on the imprinting of SARS-CoV-2 immunity

J Pušnik, WO Monzon-Posadas, E Osypchuk… - npj Vaccines, 2024 - nature.com
In the present study, Pušnik et al. investigated whether the XBB. 1.5-adapted booster can
overcome the persistent imprinting of SARS-CoV-2 immunity by wild-type based vaccines …

A long-term cohort study: the immune evasion and decreasing neutralization dominated the SARS-CoV-2 breakthrough infection

Q Liu, M Jin, F Mei, H Fan, M Gu, Y Zhang… - Frontiers in Cellular …, 2024 - frontiersin.org
Most of vaccinees and COVID-19 convalescents can build effective anti-SARS-CoV-2
humoral immunity, which helps preventing infection and alleviating symptoms. However …

[HTML][HTML] High-resolution kinetics and cellular determinants of SARS-CoV-2 antibody response over two years after COVID-19 vaccination

R Rubio, D Macià, D Barrios, M Vidal, A Jiménez… - Microbes and …, 2024 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) studies usually rely on
cross-sectional data of large cohorts but limited repeated samples, overlooking significant …

[HTML][HTML] COVID-19 vaccination in cancer patients: Immune responses one year after the third dose

R Campagna, F Dominelli, MA Zingaropoli, F Ciurluini… - Vaccine, 2024 - Elsevier
Cancer patients (CPs), being immunosuppressed due to the treatment received or to the
disease itself, are more susceptible to infections and their potential complications, showing …