Urolithiasis affects approximately 10% of individuals in Western societies by the seventh
decade of life. The most common form, idiopathic calcium oxalate urolithiasis, results from …

Context Urolithiasis has a high prevalence and recurrence rate. Prevention is key to patient
management, but risk stratification is challenging. In particular, genetic predisposition for …

Osteopontin (OPN), encoded by SPP1, is a phosphorylated glycoprotein predominantly
synthesized in kidney tissue. Increased OPN mRNA and protein expression correlates with …

Urinary stones consist of two phases—an inorganic (mineral) phase and an organic (matrix)
phase. Studies on the organic components of kidney stones have been undertaken later …

Objective: This study explores associations between recurrent kidney stones and genetic
polymorphisms. Methods: Meta-analysis of polymorphisms in renal stone cases versus …

We examined whether single nucleotide polymorphisms (SNPs) in SPP1 gene are
associated with risk of calcium oxalate urolithiasis (COU). We genotyped nine known SNPs …

Книга посвящена вопросам изучения околощитовидных желез, их развития,
физиологии, а также роли в регулировании процессов жизнедеятельности организма …

Objective. Previous studies have investigated the relationships between osteopontin gene
polymorphism rs1126616 and OPN levels and urolithiasis, but the results were …

Osteopontin (OPN) has an important role in urolithiasis. However, few studies have explored
the association between OPN genetic variants and urolithiasis risk. In the present study …

The article summarizes the findings of Russian and international studies of the genetic
aspects of polygenic urolithiasis associated with impairment of calcium metabolism. The …