[HTML][HTML] The structural dynamics, complexity of interactions, and functions in cancer of Multi-SAM containing proteins

CM Clements, MA Henen, B Vögeli, YG Shellman - Cancers, 2023 - mdpi.com
Simple Summary Cancer is a leading cause of death worldwide, with most of these deaths
being the result of tumor metastasis (spread of cancer cells from the primary site). The sterile …

[HTML][HTML] Juvenile CLN3 disease is a lysosomal cholesterol storage disorder: Similarities with Niemann-Pick type C disease

J Chen, RK Soni, Y Xu, S Simoes, FX Liang… - …, 2023 - thelancet.com
Background The most common form of neuronal ceroid lipofuscinosis (NCL) is juvenile
CLN3 disease (JNCL), a currently incurable neurodegenerative disorder caused by …

Proteomics on the role of muscone in the “consciousness-restoring resuscitation” effect of musk on ischemic stroke

B Han, Y Zhao, J Yao, N Li, T Fang, Y Wang… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Musk is a representative drug of aroma-relieving
traditional Chinese medicine, and it is a commonly used traditional Chinese medicine for the …

[HTML][HTML] The effect of sleep deprivation and subsequent recovery period on the synaptic proteome of rat cerebral cortex

P Gulyássy, K Todorov-Völgyi, V Tóth, BA Györffy… - Molecular …, 2022 - Springer
Sleep deprivation (SD) is commonplace in the modern way of life and has a substantial
social, medical, and human cost. Sleep deprivation induces cognitive impairment such as …

[HTML][HTML] A family-based study of genetic and epigenetic effects across multiple neurocognitive, motor, social-cognitive and social-behavioral functions

R Nudel, R Zetterberg, N Hemager… - Behavioral and Brain …, 2022 - Springer
Many psychiatric and neurodevelopmental disorders are known to be heritable, but studies
trying to elucidate the genetic architecture of such traits often lag behind studies of somatic …

[HTML][HTML] New insights into hypothalamic neurogenesis disruption after acute and intense stress: implications for microglia and inflammation

MI Infantes-López, A Nieto-Quero… - Frontiers in …, 2023 - frontiersin.org
In recent years, the hypothalamus has emerged as a new neurogenic area, capable of
generating new neurons after development. Neurogenesis-dependent neuroplasticity …

Replication stress causes delayed mitotic entry and chromosome 12 fragility at the ANKS1B large neuronal gene in human induced pluripotent stem cells

AV Kislova, D Zheglo, VO Pozhitnova, PS Sviridov… - Chromosome …, 2023 - Springer
Substantial background level of replication stress is a feature of embryonic and induced
pluripotent stem cells (iPSCs), which can predispose to numerical and structural …

Widespread alternative splicing dysregulation occurs presymptomatically in CAG expansion spinocerebellar ataxias

HK Shorrock, CD Lennon, A Aliyeva, EE Davey… - Brain, 2024 - academic.oup.com
The spinocerebellar ataxias (SCAs) are a group of dominantly inherited neurodegenerative
diseases, several of which are caused by CAG expansion mutations (SCAs 1, 2, 3, 6, 7 and …

Epigenomic changes after acupuncture treatment in patients suffering from burnout

M Petitpierre, L Stenz… - Complementary medicine …, 2022 - karger.com
Introduction: The effects of acupuncture treatment in patients suffering from burnout may
imply an epigenetic control mediated by DNA methylation changes. In this observational …

Полиморфные варианты генов ANKS1B rs7968606 (C> T) и ZNF804A rs1344706 (G> T) не ассоциированы с эффективностью и безопасностью применения …

ДВ Иващенко, ЮЛ Петунова, НИ Буромская… - Фарматека, 2021 - elibrary.ru
Обоснование. Фармакогенетика антипсихотиков у подростков в настоящее время
изучена недостаточно. Полиморфные варианты генов ANKS1B rs7968606 и ZNF804A …