Background Previous reports on molecular rapid diagnostic testing (mRDT) do not
consistently demonstrate improved clinical outcomes in bloodstream infections (BSIs). This …

Within the past decade, clinical microbiology laboratories experienced revolutionary
changes in the way in which microorganisms are identified, moving away from slow …

Evidence-based guidelines for implementation and measurement of antibiotic stewardship
interventions in inpatient populations including long-term care were prepared by a …

Background. The value of rapid, panel-based molecular diagnostics for positive blood
culture bottles (BCBs) has not been rigorously assessed. We performed a prospective …

Background. Integration of rapid diagnostic testing via matrix-assisted laser
desorption/ionization time-of-flight (MALDI-TOF) with antimicrobial stewardship team (AST) …

Bloodstream infections are associated with considerable morbidity and health care costs.
Molecular rapid diagnostic tests (mRDTs) are a promising complement to conventional …

Antimicrobial stewardship is a bundle of integrated interventions employed to optimize the
use of antimicrobials in health care settings. While infectious-disease-trained physicians …

In this review we examine the literature related to emerging technologies that will help to
reshape the clinical microbiology laboratory. These topics include nucleic acid amplification …

Early identification of microbial pathogens is essential for rational and conservative antibiotic
use especially in the case of known regional resistance patterns. Here, we describe …

Sepsis is a major cause of morbidity, mortality, and increased medical expense. Rapid
diagnosis improves outcomes and reduces costs. The FilmArray blood culture identification …