Photoacoustically guided wavefront shaping for enhanced optical focusing in scattering media

P Lai, L Wang, JW Tay, LV Wang - Nature photonics, 2015 - nature.com
Non-invasively focusing light into strongly scattering media, such as biological tissue, is
highly desirable but challenging. Recently, ultrasonically guided wavefront-shaping …

Focusing through dynamic tissue with millisecond digital optical phase conjugation

D Wang, EH Zhou, J Brake, H Ruan, M Jang, C Yang - Optica, 2015 - opg.optica.org
Digital optical phase conjugation (DOPC) is a new technique employed in wavefront
shaping and phase conjugation for focusing light through or within scattering media such as …

Optical focusing deep inside dynamic scattering media with near-infrared time-reversed ultrasonically encoded (TRUE) light

Y Liu, P Lai, C Ma, X Xu, AA Grabar, LV Wang - Nature communications, 2015 - nature.com
Focusing light deep inside living tissue has not been achieved despite its promise to play a
central role in biomedical imaging, optical manipulation and therapy. To address this …

Wavefront shaping and its application to enhance photoacoustic imaging

Z Yu, H Li, P Lai - Applied Sciences, 2017 - mdpi.com
Since its introduction to the field in mid-1990s, photoacoustic imaging has become a fast-
developing biomedical imaging modality with many promising potentials. By converting …

Review of current methods of acousto-optical tomography for biomedical applications

J Gunther, S Andersson-Engels - Frontiers of Optoelectronics, 2017 - Springer
The field of acousto-optical tomography (AOT) for medical applications began in the 1990s
and has since developed multiple techniques for the detection of ultrasound-modulated …

Focusing light inside dynamic scattering media with millisecond digital optical phase conjugation

Y Liu, C Ma, Y Shen, J Shi, LV Wang - Optica, 2017 - opg.optica.org
Wavefront shaping based on digital optical phase conjugation (DOPC) focuses light through
or inside scattering media, but the low speed of DOPC prevents it from being applied to …

Perspective: Wavefront shaping techniques for controlling multiple light scattering in biological tissues: Toward in vivo applications

JH Park, Z Yu, KR Lee, P Lai, YK Park - APL photonics, 2018 - pubs.aip.org
Light scattering is a fundamental physical phenomenon and also plays critical roles in
optical imaging. To optically visualize an object, waves scattered from individual positions in …

Dependence of optical scattering from Intralipid in gelatin-gel based tissue-mimicking phantoms on mixing temperature and time

P Lai, X Xu, LV Wang - Journal of biomedical optics, 2014 - spiedigitallibrary.org
Intralipid is widely used as an optical scattering agent in tissue-mimicking phantoms.
Accurate control when using Intralipid is critical to match the optical diffusivity of phantoms to …

Ultrasonically encoded wavefront shaping for focusing into random media

JW Tay, P Lai, Y Suzuki, LV Wang - Scientific reports, 2014 - nature.com
Phase distortions due to scattering in random media restrict optical focusing beyond one
transport mean free path. However, scattering can be compensated for by applying a …

Time-reversed magnetically controlled perturbation (TRMCP) optical focusing inside scattering media

Z Yu, J Huangfu, F Zhao, M Xia, X Wu, X Niu, D Li… - Scientific reports, 2018 - nature.com
Manipulating and focusing light deep inside biological tissue and tissue-like complex media
has been desired for long yet considered challenging. One feasible strategy is through …