Osteoarthritis (OA) is a leading cause of disability and its incidence is rising due to
increasing obesity and an ageing population. Risk factors can be divided into person-level …

Osteoarthritis is the most common form of arthritis, affecting millions of people in the United
States. It is a complex disease whose etiology bridges biomechanics and biochemistry …

Although the multifactorial nature of osteoarthritis (OA) is well recognized, genetic factors
have been found to be strong determinants of the disease. Evidence of a genetic influence …

Fatty acid composition in membranes plays an important role in cellular processes and has
shown to be associated with the aetiology of several complex diseases in humans. We …

Osteoarthritis (OA) is currently defined by the American College of Rheumatology as a
“heterogeneous group of conditions that leads to joint symptoms and signs which are …

Many" complex" human diseases, which involve multiple genetic and environmental
determinants, have increased in incidence during the past 2 decades. During the same time …

Osteoarthritis (OA), the most common form of arthritis, is a major contributor to functional
impairment and reduced independence in older adults. OA of the hip and knee are two of …

Osteoarthritis (OA) is a leading cause of disability in Western society with multiple risk
factors, including a complex genetic pattern. Identifying loci involved in the heredity of OA …

Tissue availability of polyunsaturated fatty acids (PUFAs) depends on dietary intake and
metabolic turnover and has a major impact on human health. Strong associations between …

Osteoarthritis (OA) is the most prevalent form of arthritis in the elderly. A large body of
evidence, including familial aggregation and classic twin studies, indicates that primary OA …