Pathobiology of Japanese encephalitis virus infection

KB Sharma, S Vrati, M Kalia - Molecular Aspects of Medicine, 2021 - Elsevier
Japanese encephalitis virus (JEV) is a flavivirus, spread by the bite of carrier Culex
mosquitoes. The subsequent disease caused is Japanese encephalitis (JE), which is the …

Automated microscopic image analysis for leukocytes identification: A survey

M Saraswat, KV Arya - Micron, 2014 - Elsevier
Automatic quantification and classification of leukocytes in microscopic images are of
paramount importance in the perspective of disease identification, its progress and drugs …

[HTML][HTML] Brain microvascular endothelial-astrocyte cell responses following Japanese encephalitis virus infection in an in vitro human blood-brain barrier model

A Patabendige, BD Michael, AG Craig… - Molecular and Cellular …, 2018 - Elsevier
Japanese encephalitis virus (JEV) remains a leading cause of encephalitis, globally, which
continues to grow in importance despite the availability of vaccines. Viral entry into the brain …

The deficient CLEC5A ameliorates the behavioral and pathological deficits via the microglial Aβ clearance in Alzheimer's disease mouse model

YY Lin, WH Chang, SL Hsieh, IHJ Cheng - Journal of Neuroinflammation, 2024 - Springer
Background Alzheimer's disease (AD) is a neurodegenerative disease that causes cognitive
dysfunction in older adults. One of the AD pathological factors, β-Amyloid (Aβ), triggers …

Nitazoxanide inhibits the replication of Japanese encephalitis virus in cultured cells and in a mouse model

Z Shi, J Wei, X Deng, S Li, Y Qiu, D Shao, B Li, K Zhang… - Virology journal, 2014 - Springer
Background Japanese encephalitis virus (JEV) has a significant impact on public health. An
estimated three billion people in'at-risk'regions remain unvaccinated and the number of …

Delivery of microRNAs by extracellular vesicles in viral infections: could the news be packaged?

FSY Yoshikawa, FME Teixeira, MN Sato, LMS Oliveira - Cells, 2019 - mdpi.com
Extracellular vesicles (EVs) are released by various cells and recently have attracted
attention because they constitute a refined system of cell–cell communication. EVs deliver a …

Alteration of blood brain barrier permeability by T-2 toxin: Role of MMP-9 and inflammatory cytokines

J Ravindran, M Agrawal, N Gupta, PVL Rao - Toxicology, 2011 - Elsevier
T-2 toxin is a cytotoxic fungal secondary metabolite produced by different species of
Fusarium such as F. sporotichioides, F. poae, F. equiseti, F. acuminatum etc. This class of …

A pan-cancer analysis reveals CLEC5A as a biomarker for cancer immunity and prognosis

R Chen, W Wu, SY Chen, ZZ Liu, ZP Wen, J Yu… - Frontiers in …, 2022 - frontiersin.org
Background CLEC5A is a member of the C-type lectin superfamily. It can activate
macrophages and lead to a series of immune-inflammation reactions. Previous studies …

Cytolytic effector pathways and IFN‐γ help protect against J apanese encephalitis

M Larena, M Regner, M Lobigs - European journal of …, 2013 - Wiley Online Library
J apanese encephalitis, caused by infection with the neurotropic flavivirus, J apanese
encephalitis virus (JEV), is among the most important viral encephalitides in A sia. While …

[HTML][HTML] The miR-9-5p/CXCL11 pathway is a key target of hydrogen sulfide-mediated inhibition of neuroinflammation in hypoxic ischemic brain injury

Y Zhao, T Li, Z Jiang, C Gai, S Yu, D Xin… - Neural Regeneration …, 2024 - journals.lww.com
We previously showed that hydrogen sulfide (H 2 S) has a neuroprotective effect in the
context of hypoxic ischemic brain injury in neonatal mice. However, the precise mechanism …