Although progesterone is a steroid hormone mainly associated with female reproductive
functions, such as uterine receptivity and maintenance of pregnancy, accumulating data …

Progesterone is a sexual steroid hormone that has a critical role in reproductive processes
in males and females of several species, including humans. Furthermore, progesterone has …

Neuroactive steroids can be synthetic or endogenous molecules produced by neuronal and
glial cells and peripheral glands. Examples include estrogens, testosterone, progesterone …

The brainstem is a posterior region of the brain, composed of three parts, midbrain, pons,
and medulla oblongata. It is critical in controlling heartbeat, blood pressure, and respiration …

Translocator protein (TSPO), a 18 kDa protein found in the outer mitochondrial membrane,
has historically been associated with the transport of cholesterol in highly steroidogenic …

Uterine leiomyomas (ULs) are the most common benign smooth muscle cell steroid-
dependent tumors that occur in women of reproductive age. Progesterone (P4) is a major …

Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide, and current treatment options are unsatisfactory on the long term. Several …

Stroke is the primary reason for death and disability worldwide, with few treatment strategies
to date. Neurosteroids, which are natural molecules in the brain, have aroused great interest …

Sex steroid hormones like estradiol (E2) and progesterone (P4) guide the sexual
organization and activation of the developing brain and control female reproductive …

Efficient in vitro differentiation into specific cell types is more important than ever after the
breakthrough in nuclear reprogramming of somatic cells and its potential for disease …