Dissemination of circulating tumor cells in breast and prostate cancer: Implications for early detection

SY Bae, KJ Kamalanathan, C Galeano-Garces… - …, 2024 - academic.oup.com
Burgeoning evidence suggests that circulating tumor cells (CTCs) may disseminate into
blood vessels at an early stage, seeding metastases in various cancers such as breast and …

Modulating cell-free DNA biology as the next frontier in liquid biopsies

S Tabrizi, C Martin-Alonso, K Xiong, SN Bhatia… - Trends in Cell …, 2024 - cell.com
Technical advances over the past two decades have enabled robust detection of cell-free
DNA (cfDNA) in biological samples. Yet, higher clinical sensitivity is required to realize the …

Role of cell-free DNA levels in the diagnosis and prognosis of sepsis and bacteremia: A systematic review and meta-analysis

MN Dadam, LT Hien, EM Makram, LV Sieu, A Morad… - Plos one, 2024 - journals.plos.org
Background Sepsis remains a major cause of mortality in intensive care units (ICUs). Prompt
diagnosis and effective management are imperative for better outcomes. In this systematic …

[HTML][HTML] The Role of Breast Milk Cell-Free DNA in the Regulation of the Neonatal Immune Response

T Rezai, S Fell-Hakai, S Guleria, G Toldi - Nutrients, 2024 - mdpi.com
The neonatal period is a critical phase for the development of the intestinal immune system,
marked by rapid adaptation to the external environment and unique nutritional demands …

cfGWAS reveal genetic basis of cell-free DNA features

H Zhu, Y Zhang, S Zeng, L Li, R Ou, X Zhang, Y Lin… - medRxiv, 2024 - medrxiv.org
cfDNA consists of degraded DNA fragments released into body fluids. Its genetic and
pathological information makes it useful for prenatal testing and early tumor detection …

Nucleic acid liquid biopsies in cardiovascular disease: Cell-free RNA liquid biopsies in cardiovascular disease

S Sharma, T Artner, KT Preissner, IM Lang - Atherosclerosis, 2024 - Elsevier
Cardiovascular diseases (CVD) and their complications continue to be the leading cause of
mortality globally. With recent advancements in molecular analytics, individualized …

Evaluation of a biomarker for amyotrophic lateral sclerosis derived from a hypomethylated DNA signature of human motor neurons

C Harvey, A Nowak, S Zhang, T Moll, AK Weimer… - 2024 - researchsquare.com
Amyotrophic lateral sclerosis (ALS) lacks a specific biomarker, but is defined by relatively
selective toxicity to motor neurons (MN). As others have highlighted, this offers an …