Copy number variation is highly correlated with differential gene expression: a pan-cancer study

X Shao, N Lv, J Liao, J Long, R Xue, N Ai, D Xu… - BMC medical …, 2019 - Springer
Background Cancer is a heterogeneous disease with many genetic variations. Lines of
evidence have shown copy number variations (CNVs) of certain genes are involved in …

17q gain in neuroblastoma: A review of clinical and biological implications

V Mlakar, I Dupanloup, F Gonzales… - Cancers, 2024 - mdpi.com
Simple Summary Neuroblastoma (NB) is the most frequent solid extracranial tumor in
children and the most frequently diagnosed cancer during infancy. A genetic modification, a …

IGF2BP1 induces neuroblastoma via a druggable feedforward loop with MYCN promoting 17q oncogene expression

S Hagemann, D Misiak, JL Bell, T Fuchs, MI Lederer… - Molecular Cancer, 2023 - Springer
Background Neuroblastoma is the most common solid tumor in infants accounting for
approximately 15% of all cancer-related deaths. Over 50% of high-risk neuroblastoma …

Copy number alteration signatures as biomarkers in cancer: a review

CG Doran, SR Pennington - Biomarkers in Medicine, 2022 - Taylor & Francis
Within certain cancers, extensive copy number alterations (CNAs) contribute to a complex
and heterogenic genomic profile. This makes it difficult to understand and unravel the …

Risk scoring based on DNA methylation-driven related DEGs for colorectal cancer prognosis with systematic insights

Z Liu, I Georgakopoulos-Soares, N Ahituv, KC Wong - Life Sciences, 2023 - Elsevier
Colorectal cancer is a common malignant tumor of the digestive tract. Despite advances in
diagnostic techniques and medications. Its prognosis remains challenging. DNA methylation …

Investigation of major genetic alterations in neuroblastoma

RA Costa, HN Seuánez - Molecular biology reports, 2018 - Springer
Neuroblastoma (NB) is the most common extracranial solid tumor in childhood. This
malignancy shows a wide spectrum of clinical outcome and its prognosis is conditioned by …

[HTML][HTML] Identification of neuroblastoma subgroups based on three-dimensional telomere organization

A Kuzyk, J Gartner, S Mai - Translational oncology, 2016 - Elsevier
Using 3D telomere quantitative fluorescence in situ hybridization, we determined the 3D
telomere organization of 74 neuroblastoma tissue samples. Hierarchical cluster analysis of …

Identification of potential biomarkers for lung adenocarcinoma

D Sayeeram, TV Katte, S Bhatia, AJ Kumar, A Kumar… - Heliyon, 2020 - cell.com
Lung adenocarcinoma (LUAD) is the most predominant subtype of lung cancers and is one
of the leading causes of cancer related mortality worldwide. Despite the advancements in …

Distinct and shared three‐dimensional chromosome organization patterns in lymphocytes, monoclonal gammopathy of undetermined significance and multiple …

C Sathitruangsak, CH Righolt, L Klewes… - … Journal of Cancer, 2017 - Wiley Online Library
The consistent appearance of specific chromosomal translocations in multiple myeloma has
suggested that the positioning of chromosomes in the interphase nucleus might play a role …

神经母细胞瘤4S 期预后不良相关因素的研究进展.

王鹏程, 董瑞 - Journal of Clinical Pediatric Surgery, 2022 - search.ebscohost.com
神经母细胞瘤(neuroblastoma, nB) 是儿童常见的颅外恶性实体肿瘤, 国际神经母细胞瘤分期
系统(Internationalneuroblastomastagingsystem, Inss) 将nB 分为I~ V 期和Vs 期, 其中Vs …