Physiology and pathophysiology in ultra-marathon running

B Knechtle, PT Nikolaidis - Frontiers in physiology, 2018 - frontiersin.org
In this overview, we summarize the findings of the literature with regards to physiology and
pathophysiology of ultra-marathon running. The number of ultra-marathon races and the …

[HTML][HTML] Physical activity and telomere length: Impact of aging and potential mechanisms of action

NC Arsenis, T You, EF Ogawa, GM Tinsley, L Zuo - Oncotarget, 2017 - ncbi.nlm.nih.gov
Telomeres protect the integrity of information-carrying DNA by serving as caps on the
terminal portions of chromosomes. Telomere length decreases with aging, and this …

Differential effects of endurance, interval, and resistance training on telomerase activity and telomere length in a randomized, controlled study

CM Werner, A Hecksteden, A Morsch… - European heart …, 2019 - academic.oup.com
Aims It is unknown whether different training modalities exert differential cellular effects.
Telomeres and telomere-associated proteins play a major role in cellular aging with …

Regular, intense exercise training as a healthy aging lifestyle strategy: preventing DNA damage, telomere shortening and adverse DNA methylation changes over a …

M Sellami, N Bragazzi, MS Prince, J Denham… - Frontiers in …, 2021 - frontiersin.org
Exercise training is one of the few therapeutic interventions that improves health span by
delaying the onset of age-related diseases and preventing early death. The length of …

Effect of physical activity, smoking, and sleep on telomere length: a systematic review of observational and intervention studies

R Barragán, C Ortega-Azorín, JV Sorli… - Journal of clinical …, 2021 - mdpi.com
Aging is a risk factor for several pathologies, restricting one's health span, and promoting
chronic diseases (eg, cardiovascular and neurodegenerative diseases), as well as cancer …

Nuclear respiratory factor 1 and endurance exercise promote human telomere transcription

A Diman, J Boros, F Poulain, J Rodriguez… - Science …, 2016 - science.org
DNA breaks activate the DNA damage response and, if left unrepaired, trigger cellular
senescence. Telomeres are specialized nucleoprotein structures that protect chromosome …

[HTML][HTML] A review of exercise as medicine in cardiovascular disease: pathology and mechanism

P Gronek, D Wielinski, P Cyganski… - Aging and …, 2020 - ncbi.nlm.nih.gov
Background Physical inactivity and resultant lower energy expenditure contribute
unequivocally to cardiovascular diseases, such as coronary artery disease and stroke …

Telomere length maintenance and cardio-metabolic disease prevention through exercise training

J Denham, BJ O'Brien, FJ Charchar - Sports medicine, 2016 - Springer
Telomeres are tandem repeat DNA sequences located at distal ends of chromosomes that
protect against genomic DNA degradation and chromosomal instability. Excessive telomere …

Genetic, environmental and lifestyle determinants of accelerated telomere attrition as contributors to risk and severity of multiple sclerosis

M Hecker, J Bühring, B Fitzner, PS Rommer, UK Zettl - Biomolecules, 2021 - mdpi.com
Telomeres are protective structures at the ends of linear chromosomes. Shortened telomere
lengths (TL) are an indicator of premature biological aging and have been associated with a …

Age and sport intensity-dependent changes in cytokines and telomere length in elite athletes

M Sellami, S Al-Muraikhy, H Al-Jaber, H Al-Amri… - Antioxidants, 2021 - mdpi.com
Exercise-associated immune response plays a crucial role in the aging process. The aim of
this study is to investigate the effect of sport intensity on cytokine levels, oxidative stress …