Divergence of Legionella effectors reversing conventional and unconventional ubiquitination

T Kitao, H Nagai, T Kubori - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
The intracellular bacterial pathogen Legionella pneumophila employs bacteria-derived
effector proteins in a variety of functions to exploit host cellular systems. The ubiquitination …

LUBAC-mediated linear ubiquitination: a crucial regulator of immune signaling

K Iwai - Proceedings of the Japan Academy, Series B, 2021 - jstage.jst.go.jp
Ubiquitination is a reversible post-translational modification in which ubiquitin chains are
conjugated to target proteins to modulate protein function. The type of ubiquitin chain …

Insights into ubiquitinome dynamics in the host‒pathogen interplay during Francisella novicida infection

L Yang, Y Li, Q Xie, T Xu, X Qi - Cell Communication and Signaling, 2024 - Springer
Ubiquitination functions as an important posttranslational modification for orchestrating
inflammatory immune responses and cell death during pathogenic infection. The …

[PDF][PDF] 一种缺失去泛素化功能的RHD1 突变体保留特异性结合线性泛素链活性

沈卓玲, 万木阳, 邓磊 - 激光生物学报, 2024 - jgsw.hunnu.edu.cn
线性泛素链连接方式特殊且被发现时间较短, 目前商用的线性泛素链特异性抗体种类少且特异性
仍有待提高. RHD1 是一种木瓜蛋白酶样去泛素化酶, 仅特异性识别线性泛素链 …