Over the past decade, traditional Chinese medicine (TCM) has widely embraced systems
biology and its various data integration approaches to promote its modernization. Thus …

Cerebrospinal fluid (CSF) flows through the central nervous system (CNS) via the
glymphatic pathway to clear the interstitium of metabolic waste. In preclinical studies …

Аннотация Современные программы лекарственной противоопухолевой терапии при
онкогематологических заболеваниях у детей предполагают проведение …

Dexmedetomidine can be used for sedation and analgesia and has been approved for this
use by the European Medicines Agency since 2017. It causes an arousable state of …

Dexmedetomidine, a highly selective α2-adrenoceptor agonist, has sedative, anxiolytic,
analgesic, sympatholytic, and opioid-sparing properties and induces a unique sedative …

The aim of this study was to compare the effects of preoperative intranasal
dexmedetomidine and oral midazolam on preoperative sedation and postoperative agitation …

Background Intraoperative opioid use has a positive relationship with postoperative nausea
and vomiting (PONV), and opioid-free anaesthesia (OFA) might reduce PONV. We …

BACKGROUND Dexmedetomidine is being used increasingly as a premedicant in the
paediatric population. However, the effectiveness of pre-operative intranasal …

Methods: In this prospective, randomised, double-blinded study, 70 adults were divided into
two groups [Group D IV (n= 35) and Group D IN (n= 35)]. D IV group received intravenous …

BACKGROUND: Our aim was to characterize the pharmacokinetics and sedative effects of
intranasally (IN) administered dexmedetomidine used as an adjuvant in pediatric patients …