Wolbachia is an endosymbiotic Alphaproteobacteria that can suppress insect-borne
diseases through decreasing host virus transmission (population replacement) or through …

Caves and other subterranean habitats fulfill the requirements of experimental model
systems to address general questions in ecology and evolution. Yet, the harsh working …

Computing in science and engineering is now ubiquitous: digital technologies underpin,
accelerate, and enable new, even transformational, research in all domains. Access to an …

Genetic pest management (GPM) methods involve releasing modified versions of a pest
species to mate with wild pests in the target area. Proposed for a wide range of applications …

Aedes mosquitoes harboring intracellular Wolbachia bacteria are being released in
arbovirus and mosquito control programs. With releases taking place around the world …

A number of recent papers report that standing genetic variation in natural populations
includes ubiquitous polymorphisms within target sites for Cas9-based gene drive (CGD) and …

Vector competence (VC) refers to the efficiency of pathogen transmission by vectors. Each
step in the infection of a mosquito vector constitutes a barrier to transmission that may …

CRISPR/Cas gene drives can bias transgene inheritance through different mechanisms.
Homing drives are designed to replace a wild-type allele with a copy of a drive element on …

The yellow fever mosquito (Aedes aegypti), is the primary vector of dengue, Zika, and
chikungunya fever, among other arboviral diseases. It is also a popular laboratory model in …

Mosquitoes carrying endosymbiotic bacteria called Wolbachia are being released in
mosquito and arbovirus control programs around the world through two main approaches …