Epidemiology, evolution, and pathogenesis of H7N9 influenza viruses in five epidemic waves since 2013 in China

S Su, M Gu, D Liu, J Cui, GF Gao, J Zhou, X Liu - Trends in microbiology, 2017 - cell.com
H7N9 influenza viruses were first isolated in 2013 and continue to cause human infections.
H7N9 infections represent an ongoing public health threat that has resulted in 1344 cases …

H7N9 influenza virus in China

C Li, H Chen - Cold Spring Harbor perspectives …, 2021 - perspectivesinmedicine.cshlp.org
In early 2013, human infections caused by a novel H7N9 avian influenza virus (AIV) were
first reported in China; these infections caused severe disease and death. The virus was …

Human infection with an avian-origin influenza A (H10N3) virus

X Qi, H Qiu, S Hao, F Zhu, Y Huang, K Xu… - … England Journal of …, 2022 - Mass Medical Soc
Human Infection with an Avian-Origin Influenza A (H10N3) Virus | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Two outbreak sources of influenza A (H7N9) viruses have been established in China

D Wang, L Yang, W Zhu, Y Zhang, S Zou, H Bo… - Journal of …, 2016 - Am Soc Microbiol
Due to enzootic infections in poultry and persistent human infections in China, influenza A
(H7N9) virus has remained a public health threat. The Yangtze River Delta region, which is …

Emerging HxNy influenza A viruses

WJ Liu, Y Wu, Y Bi, W Shi… - Cold Spring …, 2022 - perspectivesinmedicine.cshlp.org
The continuous emergence and reemergence of diverse subtypes of influenza A viruses,
which are known as “HxNy” and are mediated through the reassortment of viral genomes …

Antivirals targeting the neuraminidase

L Gubareva, T Mohan - Cold Spring …, 2022 - perspectivesinmedicine.cshlp.org
The neuraminidase (NA) of influenza A and B viruses plays a distinct role in viral replication
and has a highly conserved catalytic site. Numerous sialic (neuraminic) acid analogs that …

Screening for neuraminidase inhibitor resistance markers among avian influenza viruses of the N4, N5, N6, and N8 neuraminidase subtypes

WS Choi, JH Jeong, JJ Kwon, SJ Ahn… - Journal of …, 2018 - Am Soc Microbiol
Several subtypes of avian influenza viruses (AIVs) are emerging as novel human
pathogens, and the frequency of related infections has increased in recent years. Although …

Influenza neuraminidase mutations and resistance to neuraminidase inhibitors

J Xu, Q Luo, Y Huang, J Li, W Ye, R Yan… - Emerging Microbes & …, 2024 - Taylor & Francis
Mutations in influenza virus neuraminidase (NA) can lead to viral resistance to NA inhibitors
(NAIs). To update global influenza NA mutations and resistance to NAIs, we investigated …

Drug susceptibility evaluation of an influenza A (H7N9) virus by analyzing recombinant neuraminidase proteins

LV Gubareva, K Sleeman, Z Guo, H Yang… - The Journal of …, 2017 - academic.oup.com
Background Neuraminidase (NA) inhibitors are the recommended antiviral medications for
influenza treatment. However, their therapeutic efficacy can be compromised by NA changes …

[HTML][HTML] Functional neuraminidase inhibitor resistance motifs in avian influenza A (H5Nx) viruses

D Bialy, H Shelton - Antiviral Research, 2020 - Elsevier
Neuraminidase inhibitors (NAIs) are antiviral agents recommended worldwide to treat or
prevent influenza virus infections in humans. Past influenza virus pandemics seeded by …