Microtubules provide long tracks along which a broad range of organelles and vesicles are
transported by kinesin and dynein motors. Motor protein complexes also tether cargoes to …

Cells use molecular motors, such as myosins, to move, position and segregate their
organelles. Class V myosins possess biochemical and structural properties that should …

To establish and maintain their polarized morphology, neurons employ active transport
driven by cytoskeletal motor proteins to sort cargo between axons and dendrites. These …

Myosins are a large family of actin-based cytoskeletal motors that use energy derived from
ATP hydrolysis to generate movement and force. Myosins of classes II, V and VI have …

As the prototype of unconventional myosin motor family, myosin Va (MyoVa) transport
cellular cargos along actin filaments in diverse cellular processes. The off-duty MyoVa …

Three types of motors, myosins, kinesins, and cytoplasmic dynein, cooperate to transport
intracellular membrane organelles. Transport of each cargo is determined by recruitment of …

Chromatophores are pigment-bearing cells of lower vertebrates, including fish that cater for
the ability of individual animals to shift body coloration and pattern. Color change provides …

Formation of the human brain during embryonic and postnatal development is an
extraordinarily complex process resulting at maturity in billions of neurons with trillions of …

Pigment cells of lower vertebrates provide an excellent model to study organelle transport as
they specialize in the translocation of pigment granules in response to defined chemical …

Excitatory synapses of principal hippocampal neurons are frequently located on dendritic
spines. The dynamic strengthening or weakening of individual inputs results in structural …