[HTML][HTML] The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery and treatments
RKW Schwarting, JP Huston - Progress in neurobiology, 1996 - Elsevier
Lesions with the neurotoxin 6-hydroxydopamine (6-OHDA) have provided an important tool
to study dopamine neurons in the brain. The most common version of such lesions is the …
to study dopamine neurons in the brain. The most common version of such lesions is the …
Intracerebral adrenal medulla grafts: a review
WJ Freed, M Poltorak, JB Becker - Experimental Neurology, 1990 - Elsevier
This review summarizes basic and clinical research on intracerebral adrenal medulla grafts,
emphasizing potential applications to Parkinson's disease. Properties of intraventricular and …
emphasizing potential applications to Parkinson's disease. Properties of intraventricular and …
Striatal grafts in infarct striatopallidum increase GABA release, reorganize GABAA receptor and improve water-maze learning in the rat
N Aihara, K Mizukawa, K Koide, H Mabe… - Brain research bulletin, 1994 - Elsevier
We grafted fetal striatal cells in ischemic rat models, and investigated graft survival/growth,
GABA release, GABA A receptor reorganization and functional recovery. One hour …
GABA release, GABA A receptor reorganization and functional recovery. One hour …
Transplantation of microencapsulated bovine chromaffin cells reduces lesion-induced rotational asymmetry in rats
P Aebischer, PA Tresco, J Sagen, SR Winn - Brain research, 1991 - Elsevier
Surrounding bovine chromaffin cells by a semipermeable membrane may protect the
transplanted cells from a host immune response and shield them from the inflammatory …
transplanted cells from a host immune response and shield them from the inflammatory …
[HTML][HTML] Historical perspective of cell transplantation in Parkinson's disease
A Boronat-García, M Guerra-Crespo… - World Journal of …, 2017 - ncbi.nlm.nih.gov
Cell grafting has been considered a therapeutic approach for Parkinson's disease (PD)
since the 1980s. The classical motor symptoms of PD are caused by the loss of …
since the 1980s. The classical motor symptoms of PD are caused by the loss of …
Cografts of adrenal medulla with peripheral nerve enhance the survivability of transplanted adrenal chromaffin cells and recovery of the host nigrostriatal …
I Date, SY Felten, DL Felten - Brain research, 1990 - Elsevier
Schwann cells from transected peripheral nerve segments are known to produce nerve
growth factor (NGF). We performed adrenal medullary grafts or cografts of adrenal medulla …
growth factor (NGF). We performed adrenal medullary grafts or cografts of adrenal medulla …
Long-term survival of grafted cells, dopamine synthesis/release, synaptic connections, and functional recovery after transplantation of fetal nigral cells in rats with …
H Nishino, T Hashitani, M Kumazaki, H Sato… - Brain research, 1990 - Elsevier
In animal models of hemi-Parkinson's disease, survival of grafted nigral cells, their synaptic
connections, dopamine (DA) synthesis/release, and recovery from motor disturbances were …
connections, dopamine (DA) synthesis/release, and recovery from motor disturbances were …
[HTML][HTML] Heparin-binding epidermal growth factor-like growth factor: a component in chromaffin granules which promotes the survival of nigrostriatal dopaminergic …
M Hanke, LM Farkas, M Jakob, R Ries, J Pohl… - Neuroscience, 2004 - Elsevier
Chromaffin cells can restore function to the damaged nigrostriatal dopaminergic system in
animal models of Parkinson's disease. It has been reported that a protein which is released …
animal models of Parkinson's disease. It has been reported that a protein which is released …
Extracellular levels of serotonin in the medial pontine reticular formation in relation to sleep-wake cycle in cats: a microdialysis study
H Iwakiri, K Matsuyama, S Mori - Neuroscience research, 1993 - Elsevier
Extracellular levels of endogenous serotonin (5-hydroxytryptamine; 5-HT) and its major
metabolite, 5-hydroxyin-doleacetic acid (5-HIAA) were measured in the medial pontine …
metabolite, 5-hydroxyin-doleacetic acid (5-HIAA) were measured in the medial pontine …
[HTML][HTML] Parkinson's disease, trophic factors, and adrenal medullary chromaffin cell grafting: basic and clinical studies
I Date - Brain research bulletin, 1996 - Elsevier
Neural transplantation is one of the promising approaches for the treatment of Parkinson's
disease. Although the strategy of using adrenal medulla as donor tissue, rather than fetal …
disease. Although the strategy of using adrenal medulla as donor tissue, rather than fetal …