New frontiers in the cGAS-STING intracellular DNA-sensing pathway
S Dvorkin, S Cambier, HE Volkman, DB Stetson - Immunity, 2024 - cell.com
Summary The cGAS-STING intracellular DNA-sensing pathway has emerged as a key
element of innate antiviral immunity and a promising therapeutic target. The existence of an …
element of innate antiviral immunity and a promising therapeutic target. The existence of an …
Stimulating STING for cancer therapy: Taking the extracellular route
L Li - Cell Chemical Biology, 2024 - cell.com
Ten years ago, the second messenger cGAMP was discovered as the activator of the anti-
cancer STING pathway. The characterization of cGAMP's paracrine action and dominant …
cancer STING pathway. The characterization of cGAMP's paracrine action and dominant …