[HTML][HTML] The role of insulin/IGF1 signalling in neurodevelopmental and neuropsychiatric disorders–evidence from human neuronal cell models

JM Réthelyi, K Vincze, D Schall, J Glennon… - … & Biobehavioral Reviews, 2023 - Elsevier
Insulin and insulin-like growth factor 1 (IGF1) signalling play a central role in the
development and maintenance of neurons in the brain, and in humans neurodevelopmental …

Understanding the role of AMPA receptors in autism: insights from circuit and synapse dysfunction

A Jimenez-Gomez, MX Nguyen, JS Gill - Frontiers in Psychiatry, 2024 - frontiersin.org
Autism spectrum disorders represent a diverse etiological spectrum that converge on a
syndrome characterized by discrepant deficits in developmental domains often highlighted …

SHANK2 mutations impair apoptosis, proliferation and neurite outgrowth during early neuronal differentiation in SH-SY5Y cells

C Unsicker, FB Cristian, M von Hahn, V Eckstein… - Scientific Reports, 2021 - nature.com
SHANK2 mutations have been identified in individuals with neurodevelopmental disorders,
including intellectual disability and autism spectrum disorders (ASD). Using CRISPR/Cas9 …

Protein network analysis reveals selectively vulnerable regions and biological processes in FTD

LW Bonham, NZR Steele, CM Karch… - Neurology …, 2018 - AAN Enterprises
Objective The neuroanatomical profile of behavioral variant frontotemporal dementia
(bvFTD) suggests a common biological etiology of disease despite disparate pathologic …

Integrated Multi-Omics Analyses of Synaptosomes Revealed Synapse-Centered Novel Targets in Alzheimer's Disease

S Kumar, E Ramos, A Hidalgo, D Rodarte, B Sharma… - bioRxiv, 2025 - biorxiv.org
Synapse dysfunction is an early event in Alzheimers disease (AD) caused by various factors
such as Amyloid beta, p-tau, inflammation, and aging. However, the exact molecular …

Effects of Treadmill Exercise on Autistic Behavior and Prefrontal Cortical SHANK Receptors in Autism Spectrum Disorder Model Mice

KR Kim, TK Kim, JY Cho, KR Kim, TK Kim, JY Cho - Exercise Science, 2024 - ksep-es.org
PURPOSE The first aim of this study is to change autistic behavior in Shank3B Knock-Out
(KO) mice through treadmill exercise (TD), and the second aim is to alter SHANK protein …

Protein network analysis reveals selectively vulnerable regions and biological processes in FTD

CM Karch, N Wen, A Ofori-Kuragu - 2018 - digitalcommons.wustl.edu
Objective The neuroanatomical profile of behavioral variant frontotemporal dementia
(bvFTD) suggests a common biological etiology of disease despite disparate pathologic …

Catherine M. Rydell, CAE, Executive Director/CEO 201 Chicago Ave Minneapolis, MN 55415 Tel: 612-928-6100

KM Pieper, CS Abair, W Kluwer - Neurology, 2018 - AAN Enterprises
Copyright and Permission Information: Please go to the journal website (www. neurology.
org/nn) and click the Permissions tab for the relevant article. Alternatively, send an email to …

[引用][C] 突触后支架蛋白与神经退行性疾病

杨甜, 罗鹏 - 国际神经病学神经外科学杂志, 2016

[引用][C] Characterization and pharmaceutical treatment of the Shank3Δ11 knockout mouse model

HF Bauer - 2024 - Ulm University