Gut microbiota in COVID-19: key microbial changes, potential mechanisms and clinical applications

F Zhang, RI Lau, Q Liu, Q Su, FKL Chan… - Nature Reviews …, 2023 - nature.com
The gastrointestinal tract is involved in coronavirus disease 2019 (COVID-19) caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gut microbiota has …

Crosstalk between the gut microbiota and epithelial cells under physiological and infectious conditions

A Zhou, Y Yuan, M Yang, Y Huang, X Li, S Li… - Frontiers in Cellular …, 2022 - frontiersin.org
The gastrointestinal tract (GIT) is considered the largest immunological organ, with a diverse
gut microbiota, that contributes to combatting pathogens and maintaining human health …

Gut microbiota induces DNA methylation via SCFAs predisposing obesity-prone individuals to diabetes

W Guo, Z Zhang, L Li, X Liang, Y Wu, X Wang… - Pharmacological …, 2022 - Elsevier
Obesity-prone (OP) individuals have a significant predisposition to obesity and diabetes.
Previously, we have found that OP individuals, despite being normal in weight and BMI …

Alteration of the gut microbiota following SARS-CoV-2 infection correlates with disease severity in hamsters

V Sencio, A Machelart, C Robil, N Benech… - Gut …, 2022 - Taylor & Francis
Mounting evidence suggests that the gut-to-lung axis is critical during respiratory viral
infections. We herein hypothesized that disruption of gut homeostasis during severe acute …

Short-chain fatty acid acetate triggers antiviral response mediated by RIG-I in cells from infants with respiratory syncytial virus bronchiolitis

KH Antunes, RT Stein, C Franceschina, EF da Silva… - …, 2022 - thelancet.com
Background Gut microbiota-derived short-chain fatty-acid (SFCA) acetate protects mice
against RSV A2 strain infection by increasing interferon-β production and expression of …

Possible role of gut microbes and host's immune response in gut–lung homeostasis

S Rastogi, S Mohanty, S Sharma, P Tripathi - Frontiers in immunology, 2022 - frontiersin.org
The vast diversity of microbial communities reside in various locations of the human body,
and they are collectively named as the 'Human Microbiota.'The majority of those microbes …

Experimental models of COVID-19

LA Caldera-Crespo, MJ Paidas, S Roy… - Frontiers in cellular …, 2022 - frontiersin.org
COVID-19 is the most consequential pandemic of the 21st century. Since the earliest stage
of the 2019-2020 epidemic, animal models have been useful in understanding the …

Gut microbiota in COVID-19: new insights from inside

B Zhou, X Pang, J Wu, T Liu, B Wang, H Cao - Gut microbes, 2023 - Taylor & Francis
The epidemic of coronavirus disease-19 (COVID-19) has grown to be a global health threat.
Gastrointestinal symptoms are thought to be common clinical manifestations apart from a …

Respiratory tract infections and gut microbiome modifications: A systematic review

CA Woodall, LJ McGeoch, AD Hay, A Hammond - PLoS One, 2022 - journals.plos.org
Respiratory tract infections (RTIs) are extremely common and can cause gastrointestinal
tract symptoms and changes to the gut microbiota, yet these effects are poorly understood …

Butyrate: Connecting the gut-lung axis to the management of pulmonary disorders

RO Corrêa, PR Castro, R Moser, CM Ferreira… - Frontiers in …, 2022 - frontiersin.org
Short-chain fatty acids (SCFAs) are metabolites released by bacterial components of the
microbiota. These molecules have a wide range of effects in the microbiota itself, but also in …