Simple Summary Extracellular matrix is a three-dimensional network of macromolecules that
provide structural and biochemical support to surrounding cells. Extracellular matrix plays a …

Regenerative endodontic procedures have been described for over a decade as a paradigm
shift in the treatment of immature necrotic permanent teeth, owing to their ability to allow root …

Mesenchymal stem cell-derived exosomes regulate cell migration, proliferation,
differentiation, and synthesis of the extracellular matrix, giving great potential for the …

Matrix-bound nanovesicles (MBV) are a distinct subtype of extracellular vesicles that are
firmly embedded within biomaterials composed of extracellular matrix (ECM). MBV both …

Cytokine storm describes a life-threatening, systemic inflammatory syndrome characterized
by elevated levels of proinflammatory cytokines and immune cell hyperactivation associated …

Injuries to skeletal muscle are among the most common injuries in civilian and military
populations, accounting for nearly 60% of extremity injuries. The standard of care for severe …

Stem-cell-derived extracellular vesicles (EVs) are promising tools for therapeutic delivery
and imaging in the medical research fields. EVs that arise from endosomal compartments or …

Tissue engineering and regenerative medicine (TERM) may be defined as a translational
discipline focused on the development of novel techniques, devices, and materials to …

Aseptic loosening of orthopedic implants is an inflammatory disease characterized by
immune cell activation, chronic inflammation, and destruction of periprosthetic bone, and is …

Decellularized tissues have been used as implantable materials for tissue regeneration
because of their high biofunctionality. We have reported that high hydrostatic pressured …