[HTML][HTML] The role of cellular metabolism in maintaining the function of the dentine-pulp complex: a narrative review

K Nijakowski, M Ortarzewska, J Jankowski, A Lehmann… - Metabolites, 2023 - mdpi.com
The cellular metabolic processes ensure the physiological integrity of the dentine-pulp
complex. Odontoblasts and odontoblast-like cells are responsible for the defence …

Dentin Degradation: From Tissue Breakdown to Possibilities for Therapeutic Intervention

CMP Vidal, MR Carrilho - Current Oral Health Reports, 2023 - Springer
Abstract Purpose of the Review Presently, dental materials science is driven by the search
for new and improved materials that can trigger specific reactions from the affected tissue to …

Discriminatory performance of the pulpal inflammatory biomarkers; Interleukin‐8 and TNF‐α in patients with symptoms indicative of reversible and irreversible pulpitis …

RR Nawal, S Yadav, HF Duncan… - International …, 2024 - Wiley Online Library
Aim The success of vital pulp treatment (VPT) procedures is dependent on an accurate
diagnosis of the pulpal inflammatory condition. Compared with current subjective pulpal …

[HTML][HTML] Matrix Metalloproteinases in the Periodontium—Vital in Tissue Turnover and Unfortunate in Periodontitis

D Radzki, A Negri, A Kusiak, M Obuchowski - International Journal of …, 2024 - mdpi.com
The extracellular matrix (ECM) is a complex non-cellular three-dimensional macromolecular
network present within all tissues and organs, forming the foundation on which cells sit, and …

Co‐initiators of polymerization can modulate the inflammatory cytokine release without major cytotoxic effects in human dental pulp cells

BG Agostinelli, DC Andia… - Journal of Biomedical …, 2023 - Wiley Online Library
To evaluate the cytotoxicity of co‐initiators of polymerization and its influence on cytokine
release from human dental pulp cells (hDPCs). Cells were isolated from the dental pulp of …

Toxicity and cytokine release from human dental pulp stem cells after exposure to universal dental adhesives cured by single peak and polywave LEDs

AF Lima, AAD Oliveira, BM Fronza, RR Braga… - Dental Materials, 2024 - Elsevier
Objectives to assess the impact of universal adhesives, cured with single-peak and
polywave LEDs, on the metabolic activity and cytokine release of human dental pulp stem …

[HTML][HTML] Biochemical mapping of the inflamed human dental pulp

K Kritikou, M Imre, M Tanase, A Vinereanu, AR Totan… - Applied Sciences, 2021 - mdpi.com
Dental pulp inflammation, caused by the evolution of caries, involves numerous interrelated
activities at a cellular and molecular level. Cytokines, proteases, growth factors, and other …

Revolutionizing the diagnosis of irreversible pulpitis–Current strategies and future directions

R Bhat, S Shetty, P Rai, P Shetty - Journal of Oral Biosciences, 2024 - Elsevier
Background Pulpitis primarily arises from the pulp space infection by oral microbiota. Vital
pulp therapy is a minimally invasive approach that relies on assessing the severity of pulpal …

[HTML][HTML] Efficacy and inflammatory responses of root canal therapy plus periodontal non-surgical treatment for periodontal-endodontic combined dental lesions

Q Ye, D Wei, Z Chen, W Zhang - American Journal of Translational …, 2024 - ncbi.nlm.nih.gov
Objective: To investigate the efficacy and inflammatory responses of treating periodontal-
endodontic combined lesions (PECLs) with root canal therapy (RCT) alone versus RCT …

[HTML][HTML] Data-driven dentistry: Computational revelations redefining pulp capping

NK Kumar, VS Geervani, RSM Kumar… - Journal of …, 2024 - journals.lww.com
Aim: This in-silico study compares various Flavonoids for their anti-inflammatory effects on
MMP-9, with Chlorhexidine as a control, a known MMP-9 inhibitor. Materials and Methods …