Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infections
and hospitalization in infants under 1 year of age and there is currently no market-approved …

Pneumonia is a type of acute lower respiratory infection that is common and severe. The
outcome of lower respiratory infection is determined by the degrees to which immunity is …

As SARS-CoV-2 infections and death counts continue to rise, it remains unclear why some
individuals recover from infection, whereas others rapidly progress and die. Although the …

Development of safe and effective COVID-19 vaccines is a global priority and the best hope
for ending the COVID-19 pandemic. Remarkably, in less than 1 year, vaccines have been …

The aim of candidate universal influenza vaccines is to provide broad protection against
influenza A and B viruses. Studies have demonstrated that broadly reactive antibodies …

ABSTRACT Since 2003 (US) and 2012 (Europe) the live attenuated influenza vaccine
(LAIV) has been used as an alternative to the traditional inactivated influenza vaccines (IIV) …

The timelines for developing vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …

Antibodies play a critical role in protection against influenza; yet titers and viral neutralization
represent incomplete correlates of immunity. Instead, the ability of antibodies to leverage the …

Despite the availability of yearly vaccinations, influenza continues to cause seasonal, and
pandemic rises in illness and death. An error prone replication mechanism results in …

Vaccination remains our main defence against influenza, which causes substantial annual
mortality and poses a serious pandemic threat. Influenza virus evades immunity by rapidly …