Despite the steady increase in the number of studies focusing on the development of tissue
engineered constructs, solutions delivered to the clinic are still limited. Specifically, the lack …

Circadian rhythms govern a large array of physiological and metabolic functions.
Perturbations of the daily cycle have been linked to elevated risk of developing cancer as …

Studies in shift workers and model organisms link circadian disruption to breast cancer.
However, molecular circadian rhythms in noncancerous and cancerous human breast …

Circadian rhythms are natural rhythms that widely exist in all creatures, and regulate the
processes and physiological functions of various biochemical reactions. The circadian clock …

Background & Aims Circadian rhythms are daily physiological oscillations driven by the
circadian clock: a 24-hour transcriptional timekeeper that regulates hormones, inflammation …

The circadian clock is a regulatory system, with a periodicity of approximately 24 h, that
generates rhythmic changes in many physiological processes. Increasing evidence links …

BMAL1 is a core component of the circadian clock loop, which directs the sophisticated
circadian expression of clock-controlled genes. Skeletal Bone development is a complex …

Background To adapt to daily changes in the external environment, organisms have
developed circadian rhythm systems with a period of approximately 24 h. Many studies have …

Purpose Many brain tumor patients suffer from radiation-induced toxicities. Chronotherapy is
a treatment modality that utilizes circadian rhythms to optimize the effect on tumor while …

Background The most common breast cancer detection modalities are generally limited by
radiation exposure, discomfort, high costs, inter-observer variabilities in image interpretation …