Passive microfluidic devices for cell separation

T Zhang, D Di Carlo, CT Lim, T Zhou, G Tian… - Biotechnology …, 2024 - Elsevier
The separation of specific cell populations is instrumental in gaining insights into cellular
processes, elucidating disease mechanisms, and advancing applications in tissue …

Microfluidic formation of crystal-like structures

F Del Giudice, G D'Avino, PL Maffettone - Lab on a Chip, 2021 - pubs.rsc.org
Crystal-like structures find application in several fields ranging from biomedical engineering
to material science. For instance, droplet crystals are critical for high throughput assays and …

Beating Poisson stochastic particle encapsulation in flow-focusing microfluidic devices using viscoelastic liquids

K Shahrivar, F Del Giudice - Soft Matter, 2022 - pubs.rsc.org
The encapsulation and co-encapsulation of particles in microfluidic flows is essential in
applications related to single-cell analysis and material synthesis. However, the whole …

Controlled viscoelastic particle encapsulation in microfluidic devices

K Shahrivar, F Del Giudice - Soft Matter, 2021 - pubs.rsc.org
The encapsulation of particles in droplets using microfluidic devices finds application across
several fields ranging from biomedical engineering to materials science. The encapsulation …

Confinement effect on the viscoelastic particle ordering in microfluidic flows: Numerical simulations and experiments

A Jeyasountharan, G D'Avino, F Del Giudice - Physics of Fluids, 2022 - pubs.aip.org
Strings of equally spaced particles, also called particle trains, have been employed in
several applications, including flow cytometry and particle or cell encapsulation. Recently …

[HTML][HTML] Droplet Microfluidics for High-Throughput Screening and Directed Evolution of Biomolecules

GT Vladisavljević - Micromachines, 2024 - mdpi.com
Directed evolution is a powerful technique for creating biomolecules such as proteins and
nucleic acids with tailor-made properties for therapeutic and industrial applications by …

Microfluidic pressure-driven flow of a pair of deformable particles suspended in Newtonian and viscoelastic media: A numerical study

G Esposito, G D'Avino, MM Villone - Physics of Fluids, 2024 - pubs.aip.org
The manipulation and control of microparticles through non-intrusive methods is pivotal in
biomedical applications such as cell sorting and cell focusing. Although several …

Experimental and theoretical studies of cross-stream migration of non-spherical particles in a quadratic flow of a viscoelastic fluid

CW Tai, V Narsimhan - Soft Matter, 2022 - pubs.rsc.org
We experimentally investigate the cross-stream migration of spherical, prolate, and oblate
particles in a circular tube flow of a weakly viscoelastic fluid (De= O (10− 2)) with negligible …

Morphology, repulsion, and ordering of red blood cells in viscoelastic flows under confinement

SM Recktenwald, Y Rashidi, I Graham, PE Arratia… - Soft Matter, 2024 - pubs.rsc.org
Red blood cells (RBC), the primary carriers of oxygen in the body, play a crucial role across
several biomedical applications, while also being an essential model system of a …

[HTML][HTML] Particle migration in the flow of polymer solutions through a serpentine microchannel

S Raut, MK Raihan, Y Song, X Xuan - Physics of Fluids, 2024 - pubs.aip.org
Serpentine microchannels have been frequently used in microfluidic devices for enhanced
inertial focusing and separation of particles and cells with a reduced footprint. However …