Sepsis is a persistent systemic inflammatory condition involving multiple organ failures
resulting from a dysregulated immune response to infection, and one of the hallmarks of …

Blood-Brain Barrier (BBB) disruption is an important pathophysiological process of acute
ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic …

Objectives This study aimed to determine the effect of melatonin on thrombosis, sepsis, and
mortality rate in adult patients with severe coronavirus infection (COVID-19). Methods This …

Neutrophils are first-line responders of the innate immune system. Following myocardial
infarction (MI), neutrophils are quickly recruited to the ischemic region, where they initiate …

Neutrophil extracellular traps (NETs) are involved in the activation and dysfunction of
multiple overlapping and interacting pathways, including the immune response to injury …

From the onset of the pandemic, evidence of cardiac involvement in acute COVID-19
abounded. Cardiac presentations ranged from arrhythmias to ischemia, myopericarditis …

This article summarizes the effects of sivelestat on ALI/ARDS or ARDS with coagulopathy,
both of which are frequently seen in patients with COVID-19. The emergence of the novel …

The physiological, anti-inflammatory, and anti-coagulant properties of endothelial cells
(ECs) rely on a complex carbohydrate-rich layer covering the luminal surface of ECs, called …

Candida species are a major cause of invasive fungal infections. While Candida albicans, C.
glabrata, C. parapsilosis, and C. tropicalis are the most dominant species causing life …

Neutrophils constitute the first line of defense in human immunity and can be attracted to
inflamed and infected sites by various chemokines. As essential players in immune …