Increased intracranial pressure after neurologic injury is a clinical challenge that often
requires administration of osmotic agents. The most common osmotic agent used for …

The most common cause of acute lung injury is ischemia-reperfusion injury (IRI), during
which mitochondrial damage occurs. We have previously demonstrated that mitochondrial …

Dexamethasone (DEX) is a synthetic glucocorticoid with potent anti-inflammatory effects that
is widely used to treat inflammatory diseases. The aim of the present study was to …

T and B lymphocytes have been implicated in the pathogenesis of renal ischemia
reperfusion injury (IRI). The trafficking of lymphocytes into kidneys during IRI has been …

Healthy liver, intestine, lung, and skin harbor resident lymphocytes with conventional and
unconventional phenotypes. Lymphocytes also have been detected in healthy mice kidneys; …

OBJECTIVE: Postischemic reperfusion of the lung triggers proinflammatory responses that
stimulate injurious neutrophil chemotaxis. We hypothesized that T lymphocytes are recruited …

Acute lung injury (ALI) is an inflammatory lung disease that is caused by bacterial infection.
Lipopolysaccharide (LPS), a prototype pathogen-associated molecular pattern (PAMP) from …

Background: Cytochrome P450 epoxygenase 2J2 (CYP2J2) metabolizes arachidonic acids
to epoxyeicosatrienoic acids (EETs). EETs exert various biological effects, including anti …

T cells have been implicated in the early pathogenesis of ischemia reperfusion injury (IRI) of
kidney, liver, lung, and brain. It is not known whether Ag-TCR engagement followed by Ag …

OBJECTIVES Pulmonary ischaemia–reperfusion injury (IRI) is associated with several life-
threatening pulmonary disorders, and may severely compromise the outcome of lung …