1, 3, 5-Triazine: Recent development in synthesis of its analogs and biological profile
J Kumawat, S Jain, N Misra, J Dwivedi… - Mini-Reviews in …, 2024 - benthamdirect.com
Triazine is an important pharmacophore in the field of research for the development of novel
medications due to its presence in numerous powerful physiologically active compounds …
medications due to its presence in numerous powerful physiologically active compounds …
In silico ADMET study, docking, synthesis and antimalarial evaluation of thiazole-1, 3, 5-triazine derivatives as Pf-DHFR inhibitor
Background Plasmodium falciparum dihydrofolate reductase (Pf-DHFR) is an essential
enzyme in the folate pathway and is an important target for antimalarial drug discovery. In …
enzyme in the folate pathway and is an important target for antimalarial drug discovery. In …
Molecular insights into a mechanism of resveratrol action using hybrid computational docking/CoMFA and machine learning approach
A phytoalexin, Resveratrol remains a legendary anticancer drug candidate in the archives of
scientific literature. Although earlier wet-lab experiments rendering its multiple biological …
scientific literature. Although earlier wet-lab experiments rendering its multiple biological …
Discovery of potential 1, 3, 5-Triazine compounds against strains of Plasmodium falciparum using supervised machine learning models
The Malaria burden was an escalating global encumbrance and need to be addressed with
critical care. Anti-malarial drug discovery was integrated with supervised machine learning …
critical care. Anti-malarial drug discovery was integrated with supervised machine learning …
Insilco Study, Synthesis Of Thiazole Molecules As Possible Dihydrofolate Reductase Inhibitors Against Malaria
Heterocyclic compounds are the main class of medicinally important compounds. Many
heterocyclic compounds bearing a five-membered ring in their structure have a good …
heterocyclic compounds bearing a five-membered ring in their structure have a good …
Ligand-based pharmacophore model for generation of active antidepressant-like agents from substituted 1, 3, 5 triazine class
A Gahtori, A Singh - Current Computer-Aided Drug Design, 2020 - ingentaconnect.com
Introduction: Although the transition of a lead candidate into a drug is currently structured by
well-defined milestone, it is still most challenging and offers no guarantee in success to the …
well-defined milestone, it is still most challenging and offers no guarantee in success to the …
[PDF][PDF] Ligand Based Pharmacophore Modeling and Virtual Screening for Novel Antidiabetics Targeting PPAR-gamma
A modern sedentary lifestyle with a more calorigenic fast-food diet increasing the prevalence
of metabolic syndrome in middle and high-income countries. Peroxisome …
of metabolic syndrome in middle and high-income countries. Peroxisome …