Macrophages in immunoregulation and therapeutics

S Chen, AFUH Saeed, Q Liu, Q Jiang, H Xu… - … and Targeted Therapy, 2023 - nature.com
Macrophages exist in various tissues, several body cavities, and around mucosal surfaces
and are a vital part of the innate immune system for host defense against many pathogens …

Sex hormones in acquired immunity and autoimmune disease

VR Moulton - Frontiers in immunology, 2018 - frontiersin.org
Women have stronger immune responses to infections and vaccination than men.
Paradoxically, the stronger immune response comes at a steep price, which is the high …

[HTML][HTML] Содержание про-и противовоспалительных цитокинов в динамике экспериментального пародонтита у крыс с хроническим болевым синдромом

АЕ Брусенцова, ЮД Ляшев, НВ Цыган, ТН Елие… - …, 2022 - cyberleninka.ru
Введение. Несмотря на широкое распространение пародонтита и хронических
болевых синдромов, особенно среди пациентов среднего и старшего возраста …

The role of monocytes and macrophages in autoimmune diseases: a comprehensive review

WT Ma, F Gao, K Gu, DK Chen - Frontiers in immunology, 2019 - frontiersin.org
Monocytes (Mo) and macrophages (Mϕ) are key components of the innate immune system
and are involved in regulation of the initiation, development, and resolution of many …

The role of B cells in atherosclerosis

AP Sage, D Tsiantoulas, CJ Binder… - Nature Reviews Cardiology, 2019 - nature.com
The cardiovascular system is subject to hyperlipidaemic, inflammatory, and pro-oxidant
stressors. Over time, these factors drive prevalent chronic diseases, of which atherosclerosis …

[HTML][HTML] PD-1hiCXCR5–T peripheral helper cells promote B cell responses in lupus via MAF and IL-21

AV Bocharnikov, J Keegan, VS Wacleche, Y Cao… - JCI insight, 2019 - ncbi.nlm.nih.gov
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by pathologic
T cell–B cell interactions and autoantibody production. Defining the T cell populations that …

The maintenance of memory plasma cells

L Khodadadi, Q Cheng, A Radbruch… - Frontiers in …, 2019 - frontiersin.org
It is now well accepted that plasma cells can become long-lived (memory) plasma cells and
secrete antibodies for months, years or a lifetime. However, the mechanisms involved in this …

Inhibitory receptors and pathways of lymphocytes: the role of PD-1 in Treg development and their involvement in autoimmunity onset and cancer progression

E Gianchecchi, A Fierabracci - Frontiers in immunology, 2018 - frontiersin.org
Regulatory T (Treg) cells represent a subpopulation of suppressor CD4+ T cells critically
involved in the establishment of peripheral tolerance through the inhibition of effector T (Teff) …

B cell abnormalities in systemic lupus erythematosus and lupus nephritis—role in pathogenesis and effect of immunosuppressive treatments

DYH Yap, TM Chan - International journal of molecular sciences, 2019 - mdpi.com
Abnormalities in B cells play pivotal roles in the pathogenesis of systemic lupus
erythematosus (SLE) and lupus nephritis (LN). Breach in central and peripheral tolerance …

Cutaneous lupus erythematosus: an update on pathogenesis and future therapeutic directions

D Niebel, L de Vos, T Fetter, C Brägelmann… - American Journal of …, 2023 - Springer
Lupus erythematosus comprises a spectrum of autoimmune diseases that may affect various
organs (systemic lupus erythematosus [SLE]) or the skin only (cutaneous lupus …