Functional lung imaging in radiation therapy for lung cancer: A systematic review and meta-analysis

NW Bucknell, N Hardcastle, M Bressel… - Radiotherapy and …, 2018 - Elsevier
Rationale Advanced imaging techniques allow functional information to be derived and
integrated into treatment planning. Methods A systematic review was conducted with the …

Optimizing lung cancer radiation therapy: a systematic review of multifactorial risk assessment for radiation-induced lung toxicity

R Bensenane, S Helfre, K Cao, M Carton… - Cancer Treatment …, 2024 - Elsevier
Background Radiation therapy (RT) is essential in treating advanced lung cancer, but may
lead to radiation pneumonitis (RP). This systematic review investigates the use of pulmonary …

Measuring indirect radiation-induced perfusion change in fed vasculature using dynamic contrast CT

AE Wuschner, MJ Flakus, EM Wallat… - Journal of personalized …, 2022 - mdpi.com
Recent functional lung imaging studies have presented evidence of an “indirect effect” on
perfusion damage, where regions that are unirradiated or lowly irradiated but that are …

CT-derived vessel segmentation for analysis of post-radiation therapy changes in vasculature and perfusion

AE Wuschner, MJ Flakus, EM Wallat… - Frontiers in …, 2022 - frontiersin.org
Vessel segmentation in the lung is an ongoing challenge. While many methods have been
able to successfully identify vessels in normal, healthy, lungs, these methods struggle in the …

Radiation-induced airway changes and downstream ventilation decline in a swine model

EM Wallat, AE Wuschner, MJ Flakus… - Biomedical physics …, 2021 - iopscience.iop.org
Purpose. To investigate indirect radiation-induced changes in airways as precursors to
atelectasis post radiation therapy (RT). Methods. Three Wisconsin Miniature Swine (WMS …

Pulmonary function changes after radiotherapy for lung or esophageal cancer: a systematic review focusing on dose‐volume parameters

AGH Niezink, RA de Jong, CT Muijs… - The …, 2017 - academic.oup.com
Background Despite technical developments in treatment delivery, radiation‐induced lung
toxicity (RILT) remains a crucial problem in thoracic radiotherapy. Clinically based RILT …

Radiation-induced Hounsfield unit change correlates with dynamic CT perfusion better than 4DCT-based ventilation measures in a novel-swine model

AE Wuschner, EM Wallat, MJ Flakus… - Scientific reports, 2021 - nature.com
To analyze radiation induced changes in Hounsfield units and determine their correlation
with changes in perfusion and ventilation. Additionally, to compare the post-RT changes in …

Quantifying ventilation change due to radiation therapy using 4 DCT Jacobian calculations

TJ Patton, SE Gerard, W Shao, GE Christensen… - Medical …, 2018 - Wiley Online Library
Purpose Regional ventilation and its response to radiation dose can be estimated using four‐
dimensional computed tomography (4 DCT) and image registration. This study investigated …

[HTML][HTML] Framework for radiation pneumonitis risk stratification based on anatomic and perfused lung dosimetry

G Dhami, J Zeng, HJ Vesselle, PE Kinahan… - … und Onkologie: Organ …, 2017 - ncbi.nlm.nih.gov
Framework for radiation pneumonitis risk stratification based on anatomic and perfused lung
dosimetry - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

Comparison of regional lung perfusion response on longitudinal MAA SPECT/CT in lung cancer patients treated with and without functional tissue-avoidance radiation …

HMT Thomas, J Zeng, HJ Lee, Jr… - The British Journal of …, 2019 - academic.oup.com
Objective: The effect of functional lung avoidance planning on radiation dose-dependent
changes in regional lung perfusion is unknown. We characterized dose-perfusion response …