Reactive oxygen species (ROS) are derivatives of molecular oxygen (O 2) involved in
various physiological and pathological processes. In immune cells, ROS are mediators of …

Abstract" Life is an instantaneous encounter of circulating matter and flowing energy"(Jean
Giaja, Serbian physiologist), is one of the most elegant definitions not only of life but the …

The aim of this review was to explore the status of urine sampling as a liquid biopsy for
noninvasive cancer research by reviewing used preanalytical parameters and protocols. We …

Oxidatively generated damage to DNA has been implicated in the pathogenesis of a wide
variety of diseases. Increasingly, interest is also focusing upon the effects of damage to the …

Human xanthine oxidoreductase (XOR) catalyzes the last two steps of purine catabolism
and is present in two interconvertible forms, which may utilize O2 or NAD+ as electron …

Background: It has long been proposed that albumin, bilirubin and uric acid may inhibit
cancer development due to their anti-oxidative properties. However, there is a lack of …

Background High level of reactive oxygen species (ROS) has been detected in almost all
cancers, which make it become one of the best-characterized phenotypes in cancers …

A paradox is a seemingly absurd or impossible concept, proposition, or theory that is often
difficult to understand or explain, sometimes apparently self-contradictory, and yet ultimately …

Oxidative stress has been implicated in the initiation of several cancers, including colorectal
cancer (CRC). Whether it also plays a role in CRC prognosis is unclear. We assessed the …

Background The oxidized guanine nucleosides, 8-oxo-7, 8-dihydro-2′-deoxyguanosine (8-
oxodG) and 8-oxo-7, 8-dihydroguanosine (8-oxoGuo), derived from DNA and RNA …