Therapeutic advances in multiple sclerosis

JH Yang, T Rempe, N Whitmire, A Dunn-Pirio… - Frontiers in …, 2022 - frontiersin.org
Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system that
causes significant disability and healthcare burden. The treatment of MS has evolved over …

Immunological aspects of approved MS therapeutics

PS Rommer, R Milo, MH Han, S Satyanarayan… - Frontiers in …, 2019 - frontiersin.org
Multiple sclerosis (MS) is the most common neurological immune-mediated disease leading
to disability in young adults. The outcome of the disease is unpredictable, and over time …

Teriflunomide: a review in relapsing–remitting multiple sclerosis

LJ Scott - Drugs, 2019 - Springer
Teriflunomide (Aubagio®) is a disease-modifying immunomodulatory drug with anti-
inflammatory properties that selectively and reversibly inhibits the mitochondrial enzyme …

Personality Traits and Fatigue in Multiple Sclerosis: A Narrative Review

A Ciancio, MC Moretti, A Natale, A Rodolico… - Journal of Clinical …, 2023 - mdpi.com
(1) Background: Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune
disease. Fatigue is a prevalent and debilitating symptom that significantly impacts the quality …

Objective medication adherence and persistence in people with multiple sclerosis: a systematic review, meta-analysis, and meta-regression

J Mardan, MA Hussain, M Allan, LB Grech - Journal of Managed Care & …, 2021 - jmcp.org
BACKGROUND: Medication adherence is critical for the realization of pharmacotherapy
benefits and reduced healthcare expenditure. Studies have shown up to 60% of people with …

Beliefs about medication as predictors of medication adherence in a prospective cohort study among persons with multiple sclerosis

E Neter, L Glass-Marmor, A Wolkowitz, I Lavi, A Miller - BMC neurology, 2021 - Springer
Background Though adherence to disease-modifying therapies (DMTs) among persons with
multiple sclerosis (PwMS) varies and is often below 80%, only few prospective studies on …

Dimethyl fumarate vs Teriflunomide: an Italian time-to-event data analysis

E D'Amico, A Zanghì, M Sciandra, R Lanzillo… - Journal of …, 2020 - Springer
Background The introduction of oral disease-modifying therapies (DMTs) for relapsing–
remitting multiple sclerosis (RRMS) changed algorithms of RRMS treatment. Objectives To …

Effect of teriflunomide and dimethyl fumarate on cortical atrophy and leptomeningeal inflammation in multiple sclerosis: a retrospective, observational, case-control …

R Zivadinov, N Bergsland, E Carl… - Journal of Clinical …, 2019 - mdpi.com
Background: Pathologic changes in cortical gray matter (GM) and leptomeninges contribute
to disability worsening in patients with multiple sclerosis (MS), but there is little evidence …

Exploring polypharmacy phenomenon in newly diagnosed relapsing–remitting multiple sclerosis: A cohort ambispective single-centre study

A Zanghì, E D'Amico, S Lo Fermo… - … Advances in Chronic …, 2021 - journals.sagepub.com
Aims: We aimed to examine the frequency of polypharmacy in a large cohort of patients at
the time of diagnosis of relapsing–remitting multiple sclerosis (RRMS) and to explore its …

[HTML][HTML] Injectable versus oral first-line disease-modifying therapies: results from the Italian MS register

E D'Amico, A Zanghì, M Romeo, E Cocco… - …, 2021 - Elsevier
The current study aims to compare injectable and oral first-line disease-modifying therapies
(DMTs) for time to first relapse, time to confirmed disability progression (CDP), and time to …