Biology of saccular cerebral aneurysms: a review of current understanding and future directions

VS Fennell, MYS Kalani, G Atwal, NL Martirosyan… - Frontiers in …, 2016 - frontiersin.org
Understanding the biology of intracranial aneurysms is a clinical quandary. How these
aneurysms form, progress, and rupture is poorly understood. Evidence indicates that well …

Thrombosis in cerebral aneurysms and the computational modeling thereof: a review

MN Ngoepe, AF Frangi, JV Byrne, Y Ventikos - Frontiers in physiology, 2018 - frontiersin.org
Thrombosis is a condition closely related to cerebral aneurysms and controlled thrombosis
is the main purpose of endovascular embolization treatment. The mechanisms governing …

Predicting false lumen thrombosis in patient-specific models of aortic dissection

C Menichini, Z Cheng… - Journal of The Royal …, 2016 - royalsocietypublishing.org
Aortic dissection causes splitting of the aortic wall layers, allowing blood to enter a 'false
lumen'(FL). For type B dissection, a significant predictor of patient outcomes is patency or …

In-silico trial of intracranial flow diverters replicates and expands insights from conventional clinical trials

A Sarrami-Foroushani, T Lassila, M MacRaild… - Nature …, 2021 - nature.com
The cost of clinical trials is ever-increasing. In-silico trials rely on virtual populations and
interventions simulated using patient-specific models and may offer a solution to lower these …

The role of patient-specific morphological features of the left atrial appendage on the thromboembolic risk under atrial fibrillation

G Musotto, A Monteleone, D Vella… - Frontiers in …, 2022 - frontiersin.org
Background A large majority of thrombi causing ischemic complications under atrial
fibrillation (AF) originate in the left atrial appendage (LAA), an anatomical structure departing …

The effect of stiffened diabetic red blood cells on wall shear stress in a reconstructed 3D microaneurysm

B Czaja, J de Bouter, M Heisler… - Computer Methods in …, 2022 - Taylor & Francis
Blood flow within the vasculature of the retina has been found to influence the progression of
diabetic retinopathy. In this research cell resolved blood flow simulations are used to study …

Study and modeling of the thrombosis of small cerebral aneurysms, with and without flow diverter, by the lattice Boltzmann method

F Mezali, K Naima, S Benmamar, A Liazid - Computer Methods and …, 2023 - Elsevier
Background and objective Small cerebral aneurysms are currently commonly treated non-
invasively by flow diverter device. These stents lead to thrombotic occlusion of the aneurysm …

Evaluation of a desktop 3D printed rigid refractive-indexed-matched flow phantom for PIV measurements on cerebral aneurysms

WH Ho, IJ Tshimanga, MN Ngoepe, MC Jermy… - Cardiovascular …, 2020 - Springer
Purpose Fabrication of a suitable flow model or phantom is critical to the study of biomedical
fluid dynamics using optical flow visualization and measurement methods. The main …

Evaluation of stent effect and thrombosis generation with different blood rheology on an intracranial aneurysm by the Lattice Boltzmann method

F Mezali, S Benmamar, K Naima, H Ameur… - Computer Methods and …, 2022 - Elsevier
Background and objective Treatment of intracranial aneurysms with flow-diverting stents
prevents rupture by reducing blood flow and creating thrombosis within the aneurysm. This …

[HTML][HTML] A computational model for prediction of clot platelet content in flow-diverted intracranial aneurysms

A Sarrami-Foroushani, T Lassila, SM Hejazi… - Journal of …, 2019 - Elsevier
Abstract Treatment of intracranial aneurysms with flow-diverting stents is a safe and
minimally invasive technique. The goal is stable embolisation that facilitates stent …