Common and specific gene regulatory programs in zebrafish caudal fin regeneration at single-cell resolution

Y Chen, Y Hou, Q Zeng, I Wang, M Shang… - Genome …, 2025 - genome.cshlp.org
Following amputation, zebrafish regenerate their injured caudal fin through lineage-
restricted reprogramming. Although previous studies have charted various genetic and …

Explosive regeneration and anamorphic development of legs in the house centipede Scutigera coleoptrata

I Barutia, A Sombke - Frontiers in Zoology, 2024 - Springer
Background Regenerating legs is advantageous for arthropods as their appendages exhibit
crucial functional specializations. Many arthropods possess a 'preferred breakage point' …

Regeneration recapitulates many embryonic processes, including reuse of developmental regulatory regions

K Loubet-Senear, M Srivastava - BioRxiv, 2024 - biorxiv.org
The wide distribution of regenerative capacity across the animal tree of life raises the
question of how regeneration has evolved in distantly-related animals. Given that whole …

A cardiac transcriptional enhancer is repurposed during regeneration to activate an anti-proliferative program

A Rao, A Russell, J Segura-Bermudez… - …, 2025 - journals.biologists.com
Zebrafish have a high capacity to regenerate their hearts. Several studies have surveyed
transcriptional enhancers to understand how gene expression is controlled during heart …

A threshold level of JNK activates damage-responsive enhancers via JAK/STAT to promote tissue regeneration

JW Quinn, MC Lee, C Van Hazel, MA Wilson, RE Harris - bioRxiv, 2024 - biorxiv.org
Tissue regeneration requires the directed activity of numerous genes, which are often
reused from development. Although the identities of many key factors have been …

Inovação biomédica na cidade: estratégias para impulsionar a pesquisa em células-tronco na regeneração cerebral

LF Carvalho, FAA Rodrigues - Revista Políticas Públicas & Cidades, 2022 - journalppc.com
A baixa capacidade regenerativa do cérebro humano representa um grande desafio no
tratamento de doenças neurológicas e neurodegenerativas. Embora essas doenças …